The Endothelial Count in Pxf

NCT ID: NCT03265457

Last Updated: 2018-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-01

Study Completion Date

2020-10-01

Brief Summary

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Pseudoexfoliation Syndrome Is a common disorder in Egypt. IT is one of the common causes of coexisting cataract and glaucoma. It may be associated with a less than normal endothelial count.

Detailed Description

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The corneal Endothelium is essential for the maintenance of normal corneal hydration, thickness, and transparency.

In patients with pseudoexfoliation syndrome , quantitative and qualitative morphological changes of the corneal endothelium have been demonstrated in specular and electron microscopic studies.

Specular microscopy is a non-invasive technique to access the structure and function of the corneal endothelium.

Our research question is to study Endothelial cell count in patients with pseudoexfoliation syndrome \& compare it to age matched group.

Conditions

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Pseudoexfoliation Syndrome

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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patient with pseudoexfoliation syndrome

The corneal Endothelial cell count will be measured by specular microscopy

Specular microscopy

Intervention Type OTHER

Comparison between corneal Endothelial count in patients with pseudoexfoliation syndrome and age matched group

Normal people at same age

Specular microscopy

Intervention Type OTHER

Comparison between corneal Endothelial count in patients with pseudoexfoliation syndrome and age matched group

Interventions

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Specular microscopy

Comparison between corneal Endothelial count in patients with pseudoexfoliation syndrome and age matched group

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with pseudoexfoliation syndrome

Exclusion Criteria

* Patients with previous intra ocular surgeries.
* Patients with uveitis
* Patients with fuck's endothelial dystrophy
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Amira Asem

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Miyake K, Matsuda M, Inaba M. Corneal endothelial changes in pseudoexfoliation syndrome. Am J Ophthalmol. 1989 Jul 15;108(1):49-52. doi: 10.1016/s0002-9394(14)73259-3.

Reference Type BACKGROUND
PMID: 2750833 (View on PubMed)

Other Identifiers

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PXF

Identifier Type: -

Identifier Source: org_study_id

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