Relationships Between Macular Pigment Optical Density and Lacquer Cracks in High Myopic Patients.

NCT ID: NCT02205632

Last Updated: 2018-04-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-02-28

Study Completion Date

2014-11-30

Brief Summary

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Lutein ans zeaxanthin, carotenoids provided by dietary intake are mainly located in the macular area.

Its absorption peak at 460 nm may reduce photic damages. The macular pigment density can be evaluated by its optical density.

Reduced macular pigment level is a significant risk factor for age-macular degeneration. The nutritional intake can minimise the risk of age-macular degeneration.

Detailed Description

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Conditions

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High Myopia

Study Design

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Allocation Method

NON_RANDOMIZED

Blinding Strategy

NONE

Study Groups

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High myopic patients with lacker craks

Group Type OTHER

MPS II

Intervention Type DEVICE

High myopic patients without lacker cracks

Group Type OTHER

MPS II

Intervention Type DEVICE

Interventions

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MPS II

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age \>18 years-old
* High axial myopia \< -6 dioptries
* Presence or not of lacquer cracks in Bruch's membrane in one or both eyes
* Patients with social security coverage

Exclusion Criteria

* Age \<18 years-old
* Amblyopia in the studied eye
* Prior ocular surgery
* Corneal disease or severe dry eye syndrome
* Other retinal disease: diabetic retinopathy, age-related macular degeneration, macular hole, epiretinal membrane central
* Extensive chorioretinal atrophy
* Allergy to tropicamide
* Pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Poitiers University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nicolas LEVEZIEL, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Poitiers University Hospital

Locations

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ophthalmology department, Poitiers University Hospital

Poitiers, Vienne, France

Site Status

Countries

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France

Other Identifiers

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MPSII-RMB

Identifier Type: -

Identifier Source: org_study_id

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