Study to Observe the Change in Microbiome in Human Derived Sample and the Relation With Clinical Response Before and After the Anti-TNF Treatment in IBD Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-09-21

Study Completion Date

2020-01-16

Brief Summary

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This study will be conducted to observe the difference in microbiome composition between healthy participants and inflammatory bowel disease (IBD) participants with no anti-tumor necrosis factor (anti-TNF) treatment.

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Detailed Description

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Conditions

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Inflammatory Bowel Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Microbial composition measured from IBD and non-IBD groups

Participants with inflammatory bowel disease (IBD) and non-IBD will be measured for microbial composition.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Male or female, age ≥ 19 years at the time of informed consent
* Confirmed diagnosis of IBD
* Participants who are naïve to anti-tumour necrosis factor (anti-TNF)

* Participants who have not been diagnosed with IBD
* Participants who don't have any other intestinal disease except IBD
* Participants who are naïve to anti-TNF

Exclusion Criteria

* Contraindication to anti-TNF including active tuberculosis (TB), sepsis, or other severe opportunistic infection, etc.

* Participants who have been on medication to treat underlying disease for the previous 3 months

Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes