Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-02-29

Study Completion Date

2017-06-30

Brief Summary

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Infertility is defined as a couple's inability to become pregnant after one year of unprotected intercourse in women 35 years old and younger, and for six months in women over age 35 years. In any given year, about 15 percent of couples in North America and Europe who are trying to conceive are infertile

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Detailed Description

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Conditions

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Infertility

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Lertozole

oral tablets 5 mg start from third day cycle for 5 days

Group Type EXPERIMENTAL

Letrozole

Intervention Type DRUG

oral tablets 5 mg

clomiphene plus N- acetyl cystiene

clomiphene 100 mg plus N-acetyl cystiene 600 mg start from third day cycle for 5 days

Group Type ACTIVE_COMPARATOR

Clomiphene Citrate plus N acetyl cystine

Intervention Type DRUG

Clomiphene Citrate 100 mg oral tablets+ N acetyl cystiene 600 mg

Interventions

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Letrozole

oral tablets 5 mg

Intervention Type DRUG

Clomiphene Citrate plus N acetyl cystine

Clomiphene Citrate 100 mg oral tablets+ N acetyl cystiene 600 mg

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* All primary and secondary. Infertility due to anovulation

Exclusion Criteria

* Male factor infertility, tubal factor.
* Endocrineopathy
* Hypothyrodism
* Morbid obesity
* Under weight
* Patient with previous surgery including drilling of ovary, Clomiphene Citrate resistant to ovulation.

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No