Characterization of the Facial and Gut Microbiome in Rosacea
NCT ID: NCT03228927
Last Updated: 2017-07-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
150 participants
OBSERVATIONAL
2017-08-05
2017-08-06
Brief Summary
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Detailed Description
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2. Subjects will be examined by a board-certified dermatologist and global assessment, inflammatory counts and clinician's erythema score will be performed. Eyes will be examined for signs of ocular rosacea.
3. Facial microbiome sampling will be performed on-site utilizing a kit manufactured by UBiome. The skin with active rosacea will be swabbed and the swab immediately placed in sample medium. The tube is then shipped to the manufacturer for 16s rRNA shotgun metagenomics to identify resident bacterial genera and species. (16) This can be compared to their extensive library of normal controls, to the other member of the twin set and to acne subjects.
4. Subjects will be given a fecal microbiome kit for home sampling. Feces obtained from toilet paper is collected and placed in the sample medium. Subjects can either ship directly or return to the study site for shipping.
Conditions
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Study Design
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COHORT
CROSS_SECTIONAL
Study Groups
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twin A
Sampling of the facial and fecal microbiome
comparison of twin A to twin B
Comparison of Twin A to Twin B
twin B
Sampling of the facial and fecal microbiome
comparison of twin A to twin B
Comparison of Twin A to Twin B
Interventions
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comparison of twin A to twin B
Comparison of Twin A to Twin B
Eligibility Criteria
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Inclusion Criteria
2. One or both twins with facial rosacea
3. Willingness to allow facial and fecal samples to be analyzed -
Exclusion Criteria
2. Absence of facial rosacea in both twins -
ALL
No
Sponsors
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The Acne Cure Alliance
OTHER
Responsible Party
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Hilary Baldwin
Medical Director
Other Identifiers
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713
Identifier Type: -
Identifier Source: org_study_id
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