Study to Evaluate the Long-term Safety of a Once-Daily Omiganan Topical Gel

NCT ID: NCT02576847

Last Updated: 2022-07-19

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

307 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-10-31

Study Completion Date

2018-02-08

Brief Summary

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This study evaluates the long-term safety of once-daily application of Omiganan topical gel in subjects with severe papulopustular rosacea.

Detailed Description

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Conditions

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Rosacea

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Treatment

Omiganan gel applied once daily

Group Type EXPERIMENTAL

Omiganan

Intervention Type DRUG

Topical gel

Interventions

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Omiganan

Topical gel

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Healthy, male and nonpregnant female subjects, 18 years of age or older.
2. A diagnosis of severe papulopustular rosacea using the Investigator Global Assessment grading scale at baseline
3. Subjects with the presence of telangiectasia at Baseline
4. Subjects with the presence of facial erythema associated with their rosacea at Baseline

Exclusion Criteria

1. Subjects with steroid rosacea or subtype 3 (phymatous rosacea).
2. Subjects with nodular rosacea
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Maruho Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Fremont, California, United States

Site Status

Miami, Florida, United States

Site Status

Miramar, Florida, United States

Site Status

Tampa, Florida, United States

Site Status

Arlington Heights, Illinois, United States

Site Status

Carmel, Indiana, United States

Site Status

Indianapolis, Indiana, United States

Site Status

Plainfield, Indiana, United States

Site Status

Watertown, Massachusetts, United States

Site Status

Albuquerque, New Mexico, United States

Site Status

New York, New York, United States

Site Status

Nashville, Tennessee, United States

Site Status

Dallas, Texas, United States

Site Status

Pflugerville, Texas, United States

Site Status

Webster, Texas, United States

Site Status

Sydney, New South Wales, Australia

Site Status

Woolloongabba, Queensland, Australia

Site Status

Vancouver, British Columbia, Canada

Site Status

Winnipeg, Manitoba, Canada

Site Status

Drummondville, Quebec, Canada

Site Status

Cannes, , France

Site Status

Nice, , France

Site Status

Bergen op Zoom, , Netherlands

Site Status

Hamilton, , New Zealand

Site Status

Wellington, , New Zealand

Site Status

Gothenburg, , Sweden

Site Status

Lanarkshire, , United Kingdom

Site Status

Manchester, , United Kingdom

Site Status

Countries

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United States Australia Canada France Netherlands New Zealand Sweden United Kingdom

References

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You Y, Liu H, Zhu Y, Zheng H. Rational design of stapled antimicrobial peptides. Amino Acids. 2023 Apr;55(4):421-442. doi: 10.1007/s00726-023-03245-w. Epub 2023 Feb 12.

Reference Type DERIVED
PMID: 36781451 (View on PubMed)

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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CLS001-CO-PR-006

Identifier Type: -

Identifier Source: org_study_id

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