A Study to Evaluate the Safety and Efficacy of Omiganan (CLS001) Topical Gel Versus Vehicle in Female Subjects With Moderate to Severe Acne Vulgaris

NCT ID: NCT02571998

Last Updated: 2017-03-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

320 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-10-31

Study Completion Date

2016-08-31

Brief Summary

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The primary objective of this study is to evaluate the safety and efficacy of Omiganan (CLS001) topical gel compared to vehicle topical gel applied once daily for 12 weeks in female subjects with moderate to severe inflammatory acne vulgaris.

Detailed Description

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Conditions

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Acne Vulgaris

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Treatment

Omiganan (CLS001) Topical Gel applied once daily

Group Type EXPERIMENTAL

Omiganan (CLS001) Topical Gel

Intervention Type DRUG

Vehicle Gel

Vehicle Topical Gel applied once daily

Group Type PLACEBO_COMPARATOR

Vehicle Topical Gel

Intervention Type DRUG

Interventions

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Omiganan (CLS001) Topical Gel

Intervention Type DRUG

Vehicle Topical Gel

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Non-pregnant female subjects ≥ 12 years of age with facial acne vulgaris
* Subjects with an Investigator's Global Assessment (IGA) of Inflammatory Lesions of Acne Vulgaris of Moderate (3) or Severe (4) at Baseline.
* Subjects with ≥ 30 facial inflammatory lesions

Exclusion Criteria

* Subjects with \< 10 or \> 75 facial non-inflammatory lesions
* Subjects with \> 3 facial nodular or cystic lesions at Baseline
Minimum Eligible Age

12 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Maruho Co., Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Mobile, Alabama, United States

Site Status

Phoenix, Arizona, United States

Site Status

Santa Ana, California, United States

Site Status

Santa Monica, California, United States

Site Status

Denver, Colorado, United States

Site Status

Boca Raton, Florida, United States

Site Status

Boynton Beach, Florida, United States

Site Status

Miami, Florida, United States

Site Status

Pinellas Park, Florida, United States

Site Status

Sanford, Florida, United States

Site Status

Tampa, Florida, United States

Site Status

Beverly, Massachusetts, United States

Site Status

Fort Gratiot, Michigan, United States

Site Status

St Louis, Missouri, United States

Site Status

Las Vegas, Nevada, United States

Site Status

Newington, New Hampshire, United States

Site Status

Albuquerque, New Mexico, United States

Site Status

New York, New York, United States

Site Status

Stony Brook, New York, United States

Site Status

High Point, North Carolina, United States

Site Status

Raleigh, North Carolina, United States

Site Status

Knoxville, Tennessee, United States

Site Status

Arlington, Texas, United States

Site Status

Austin, Texas, United States

Site Status

Pflugerville, Texas, United States

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San Antonio, Texas, United States

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Webster, Texas, United States

Site Status

Salt Lake City, Utah, United States

Site Status

Spokane, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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CLS001-CO-PR-009

Identifier Type: -

Identifier Source: org_study_id

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