A Therapeutic Equivalence Study of Two Metronidazole Gel 1% Topical Treatments of Rosacea

NCT ID: NCT02393937

Last Updated: 2020-09-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

963 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Study Completion Date

2015-10-31

Brief Summary

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The purpose of this study is to compare the efficacy of two Metronidazole Gels 1%, in the treatment of Rosacea.

Detailed Description

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Conditions

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Papulopustular Rosacea Erythematotelangiectatic Rosacea

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Test: Metronidazole Gel 1%

Metronidazole Gel 1% once daily for 70 days.

Group Type EXPERIMENTAL

Test: Metronidazole Gel 1%

Intervention Type DRUG

Participants are assigned to one of three groups in parallel for the duration of the study

Reference: Metronidazole Gel 1%

Metronidazole Gel, 1% (MetroGel) Galderma S.A. once daily for 70 days.

Group Type ACTIVE_COMPARATOR

Reference: Metronidazole Gel 1%

Intervention Type DRUG

Participants are assigned to one of three groups in parallel for the duration of the study

Placebo

Placebo Gel once daily for 70 days.

Group Type PLACEBO_COMPARATOR

Placebo Gel

Intervention Type DRUG

Participants are assigned to one of three groups in parallel for the duration of the study

Interventions

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Reference: Metronidazole Gel 1%

Participants are assigned to one of three groups in parallel for the duration of the study

Intervention Type DRUG

Test: Metronidazole Gel 1%

Participants are assigned to one of three groups in parallel for the duration of the study

Intervention Type DRUG

Placebo Gel

Participants are assigned to one of three groups in parallel for the duration of the study

Intervention Type DRUG

Other Intervention Names

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MetroGel

Eligibility Criteria

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Inclusion Criteria

* Male or Female subjects with at least 18 years of age;
* Read and signed ICF;
* Clinical Diagnosis of Rosacea;

Exclusion Criteria

* Females who are pregnant, lactating or of childbearing potential who are not using or do not agree to use an acceptable form of contraception;
* Any skin condition that would interfere with treatment of rosacea
* Use of prohibited medications
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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bioRASI, LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Los Angeles, California, United States

Site Status

San Diego, California, United States

Site Status

Boca Raton, Florida, United States

Site Status

Clearwater, Florida, United States

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Miami, Florida, United States

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Miami, Florida, United States

Site Status

Miramar, Florida, United States

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Ocala, Florida, United States

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Tampa, Florida, United States

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Lexington, Kentucky, United States

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Watertown, Massachusetts, United States

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Las Vegas, Nevada, United States

Site Status

New York, New York, United States

Site Status

High Point, North Carolina, United States

Site Status

Raleigh, North Carolina, United States

Site Status

Cincinnati, Ohio, United States

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Philadelphia, Pennsylvania, United States

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Warwick, Rhode Island, United States

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Mt. Pleasant, South Carolina, United States

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Austin, Texas, United States

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El Paso, Texas, United States

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Houston, Texas, United States

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Pflugerville, Texas, United States

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Plano, Texas, United States

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San Antonio, Texas, United States

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Arlington, Virginia, United States

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Norfolk, Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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LO-17-3-2014

Identifier Type: -

Identifier Source: org_study_id

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