Oxytocin and Non-verbal Communication

NCT ID: NCT03228901

Last Updated: 2017-07-27

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE2
• Total Enrollment: 104 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2007-01-31
• Study Completion Date: 2009-07-31

Brief Summary

In this protocol registration, the investigators plan a secondary data analysis of a dataset to explore the effects of intra-nasal oxytocin on the non-verbal expression of affiliation.

Detailed Description

Using Liu et al.'s (2012) dataset, the investigators seek to observe whether the administration of oxytocin modifies non-verbal communication with a stranger.

This dataset involves a conversation between two strangers that took place 45 minutes after drug administration. While Liu et al. coded the video for markers of interpersonal distance (physical distance, eye contact, conversational intimacy), the investigators seek to analyse oxytocin's effects on non-verbal communication of affiliative and sexual cues (e.g., smiles, lip puckers). Based on findings that oxytocin's effects depend on context, the investigators will explore these relationships as a function of the conversational context (where participants converse with each other using low-, medium-, and high-intimacy topics, or in an unstructured conversation).

Conditions

Social Interaction

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: FACTORIAL
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: TRIPLE

Study Groups

Oxytocin

24IU Syntocinon, delivered in a single nose via a nasal spray

Group Type: EXPERIMENTAL

Oxytocin

Intervention Type: DRUG

Administration of the hormone oxytocin

Placebo

Matched nasal spray

Group Type: PLACEBO_COMPARATOR

Placebos

Intervention Type: DRUG

Interventions

Oxytocin

Administration of the hormone oxytocin

Intervention Type: DRUG

Placebos

Intervention Type: DRUG

Other Intervention Names

Syntocinon

Eligibility Criteria

Inclusion Criteria

• healthy

Exclusion Criteria

• pregnant;
• history of epilepsy, severe depression, severe anxiety, or psychosis;
• smoking more than 15 cigarettes a day;
• addicted to illegal substances.

• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Yale-NUS College

OTHER

Sponsor Role: lead

Responsible Party

Jean Liu

Assistant Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

University of New South Wales

Sydney, New South Wales, Australia

Countries

Australia

Other Identifiers

IG15-B052

Identifier Type: -

Identifier Source: org_study_id