Radiofrequency Neurotomy In Relieving Chronic Knee Pain

NCT ID: NCT03224637

Last Updated: 2017-07-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-07-31

Study Completion Date

2016-02-29

Brief Summary

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Osteoarthritis (OA) affects aged above 45 years. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities. It was also used for the treatment of painful conditions of the hip joint.

Detailed Description

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Osteoarthritis (OA) is commonest chronic arthritis affecting patients usually aged above 45 years. OA decreased health-related quality of life and increased economic costs. Radiofrequency (RF), was used for the treatment of chronic pain unresponsive to conservative therapies. RF has been used for several painful conditions. There have been a few attempts to use RF current for the treatment of painful conditions of joints of the extremities. It was also used for the treatment of painful conditions of the hip joint.

Conditions

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Osteo Arthritis Knee Pain, Chronic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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radiofrequency group

radiofrequency was done in the three genicular nerves upper medial and upper lateral and lower medial

Group Type ACTIVE_COMPARATOR

radiofrequency

Intervention Type PROCEDURE

radiofrequency done in the three genicular nerves upper medial and upper lateral and lower medial

conventional group

the patients received conventional paracetamol and non steroidal antiinflammatory

Group Type ACTIVE_COMPARATOR

Paracetamol (conventional)

Intervention Type DRUG

Ketorolac Tromethamine (conventional)

Intervention Type DRUG

Interventions

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radiofrequency

radiofrequency done in the three genicular nerves upper medial and upper lateral and lower medial

Intervention Type PROCEDURE

Paracetamol (conventional)

Intervention Type DRUG

Ketorolac Tromethamine (conventional)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* chronic arthritis according to the American College of Rheumatology criteria
* diagnosed radiologically patients in stage 3 and 4, according to the Kellgren-Lawrence classification

Exclusion Criteria

* other causes of pain such as radiculopathy, neurological disorders, or intermittent claudication.
* patients receive intraarticular steroid or hyaluronic acids during previous three months.
* patients did previous knee surgery.
* Patients with general contraindication to the application of invasive intervention such as hemorrhage, coagulation disorder, systemic infection or local infection.
* patients with other connective tissue disease affecting the knee. And 6-psychiatric disorders.
Minimum Eligible Age

30 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Emad Zarief , MD

Lecturer of Anesthesia and ICU

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Emad Zarief Kamel Said

Asyut, , Egypt

Site Status

Countries

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Egypt

References

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El-Hakeim EH, Elawamy A, Kamel EZ, Goma SH, Gamal RM, Ghandour AM, Osman AM, Morsy KM. Fluoroscopic Guided Radiofrequency of Genicular Nerves for Pain Alleviation in Chronic Knee Osteoarthritis: A Single-Blind Randomized Controlled Trial. Pain Physician. 2018 Mar;21(2):169-177.

Reference Type DERIVED
PMID: 29565947 (View on PubMed)

Other Identifiers

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IRB00009913

Identifier Type: -

Identifier Source: org_study_id

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