Prediction of Sudden Cardiac Death in Dilated Cardiomyopathy
NCT ID: NCT03224156
Last Updated: 2017-07-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
150 participants
OBSERVATIONAL
2017-07-31
2019-07-31
Brief Summary
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Detailed Description
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CMR provides unique information on myocardial mechanics, fibrotic burden, inflammation and microvascular dysfunction, thereby allowing to quantify key substrates for myocardial arrhythmogenic potential.
PREDICT-DCM Trial is a multi-centre, prospective observational trial including patients with DCM undergoing cardiac magnetic resonance imaging (CMR) prior to ICD or event recorder implantation.
Acquired candidate predictors are among others:
* Global and regional T1/T2
* T1/T2 inhomogeneity
* Extracellular volume fraction
* Microvascular dysfunction
* LA function and filling fraction
* Global and regional circumferential, radial or longitudinal myocardial strain
* Biomarkers
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Dilated Cardiomyopathy
Cardiac Magnetic Resonance Imaging
Patients undergo baseline characterisation including CMR, ECG, blood samples prior to ICD implantation.
Interventions
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Cardiac Magnetic Resonance Imaging
Patients undergo baseline characterisation including CMR, ECG, blood samples prior to ICD implantation.
Eligibility Criteria
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Inclusion Criteria
* ICD Indication
* age ≥ 18 years
* signed informed consent
Exclusion Criteria
* rest dyspnea
* tachycardia or severe arrhythmia
* intolerance to gadolinium-based contrast agent
18 Years
75 Years
ALL
No
Sponsors
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University Hospital Heidelberg
OTHER
Responsible Party
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Marco Ochs
Dr. med. Marco Ochs
Locations
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University Hospital Heidelberg, Krehl Klinik, Department of Cardiology
Heidelberg, Baden-Wurttemberg, Germany
GRN Hospital Weinheim
Weinheim, Baden-Wurttemberg, Germany
Countries
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Central Contacts
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Facility Contacts
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Marco M Ochs, Dr. med.
Role: primary
Sorin Giusca, Dr. med.
Role: primary
Related Links
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University Hospital Heidelberg
Other Identifiers
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S-281/2017
Identifier Type: -
Identifier Source: org_study_id
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