A Study of Use of Ella®, an Emergency Contraceptive, Under Simulated OTC Conditions

NCT ID: NCT03208985

Last Updated: 2022-12-02

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

1270 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-05-23

Study Completion Date

2018-06-14

Brief Summary

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This study is designed to assess whether consumers select and use ella® (ulipristal acetate 30mg), an emergency contraceptive, in a manner consistent with the OTC package directions in an OTC-like setting.

Detailed Description

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All potential subject coming to a site looking to purchase EC will be offered to participate in the study. Subjects who meet the initial screening inclusion criteria for the study will review package information and make a self-selection and purchase decision. Subjects who meet all remaining inclusion criteria will purchase ella®, and use based on their understanding of the package information.

Follow-up data regarding product use and adverse events will be obtained during telephone interviews at approximately Week-2 and Week-6 after the date the subject was dispensed study product.

Conditions

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Emergency Contraception

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Use Phase (Ulipristal Acetate, 30 mg)

One tablet of 30 mg of ulipristal acetate for emergency contraception

Group Type EXPERIMENTAL

Use Phase (Ulipristal Acetate, 30 mg)

Intervention Type DRUG

All subjects enrolled in the use phase of this open-label study will be given the opportunity to purchase and take 30 mg of ulipristal acetate.

Subjects are to use the investigational product based on their understanding of the directions on the outer packaging including Drug Facts Label and inside the product packaging (in the Consumer Information Leaflet).

Interventions

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Use Phase (Ulipristal Acetate, 30 mg)

All subjects enrolled in the use phase of this open-label study will be given the opportunity to purchase and take 30 mg of ulipristal acetate.

Subjects are to use the investigational product based on their understanding of the directions on the outer packaging including Drug Facts Label and inside the product packaging (in the Consumer Information Leaflet).

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Women who are self-pay or who are willing to be self-pay for the purposes of the study and who present for emergency contraception only for their own use

Exclusion Criteria

* Cannot read, speak and understand English
* Cannot see well enough to read information on the label
Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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HRA Pharma

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Russel Bradford, MD, MSPH

Role: PRINCIPAL_INVESTIGATOR

Pegus Research, Inc.

Locations

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HRA Pharma Investigational Site

Rancho Cucamonga, California, United States

Site Status

HRA Pharma Investigational Site

Boulder, Colorado, United States

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HRA Pharma Investigational Site

Denver, Colorado, United States

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HRA Pharma Investigational Site

Denver, Colorado, United States

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HRA Pharma Investigational Site

Fort Myers, Florida, United States

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HRA Pharma Investigational Site

Miami, Florida, United States

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HRA Pharma Investigational Site

Orlando, Florida, United States

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HRA Pharma Investigational Site

Pembroke Pines, Florida, United States

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HRA Pharma Investigational Site

St. Petersburg, Florida, United States

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HRA Pharma Investigational Site

Tampa, Florida, United States

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HRA Pharma Investigational Site

Belleville, Illinois, United States

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HRA Pharma Investigational Site

Andover, Minnesota, United States

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HRA Pharma Investigational Site

Saint Louis Park, Minnesota, United States

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HRA Pharma Investigational Site

City of Saint Peters, Missouri, United States

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HRA Pharma Investigational Site

Kansas City, Missouri, United States

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HRA Pharma Investigational Site

Manchester, Missouri, United States

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HRA Pharma Investigational Site

St Louis, Missouri, United States

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HRA Pharma Investigational Site

St Louis, Missouri, United States

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HRA Pharma Investigational Site

Las Vegas, Nevada, United States

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HRA Pharma Investigational Site

Hackensack, New Jersey, United States

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HRA Pharma Investigational Site

Morristown, New Jersey, United States

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HRA Pharma Investigational Site

New Brunswick, New Jersey, United States

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HRA Pharma Investigational Site

Trenton, New Jersey, United States

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HRA Pharma Investigational Site

Albuquerque, New Mexico, United States

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HRA Pharma Investigational Site

Albuquerque, New Mexico, United States

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HRA Pharma Investigational Site

New York, New York, United States

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HRA Pharma Investigational Site

Durham, North Carolina, United States

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HRA Pharma Investigational Site

Raleigh, North Carolina, United States

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HRA Pharma Investigational Site

Portland, Oregon, United States

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HRA Pharma Investigational Site

Bremerton, Washington, United States

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HRA Pharma Investigational Site

Puyallup, Washington, United States

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HRA Pharma Investigational Site

Seattle, Washington, United States

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HRA Pharma Investigational Site

Seattle, Washington, United States

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HRA Pharma Investigational Site

Tacoma, Washington, United States

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Countries

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United States

Provided Documents

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Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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151032-001

Identifier Type: -

Identifier Source: org_study_id

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