High-flow Nasal Oxygenation in Obese Patients During Apnea

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-08-10

Study Completion Date

2018-04-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Before going off to sleep patients are given oxygen to saturate blood with oxygen to extend time before a decrease in the level of oxygen in the blood occurs. During this period, obese patients have a faster decrease in the level of oxygen in their blood. This study uses a device called "high-flow nasal cannula" (HFNC), which delivers humidified high-flow oxygen through 2 small plastic tubes placed just inside nostrils. In the intensive care unit settings this device has been used extensively and has become a standard practice. Purpose of this study is to determine whether these high-flow nasal cannula increase the time safely when going to sleep during elective surgery.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

CPAP/PSV Preoxygenation in Obese Patients

NCT01780571

Obesity Anaesthesia

COMPLETED NA

Ventilation Distribution After Bariatric Surgery

NCT03975348

Bariatric Surgery Candidate Atelectasis, Postoperative Pulmonary

COMPLETED NA

Preoxygenation Optimisation in Obese Patients

NCT03106441

Severe Obesity Design as BMI > 35kg/m2

COMPLETED NA

Oxygenation Procedure for Obese Patients During Intubation in the Operating Room

NCT06914401

Anesthesia Induction

RECRUITING NA

High-flow Nasal Oxygen Therapy in Obese Patients Undergoing Sedative Gastroscopy

NCT06585306

Hypoxia Obesity Gastrostomy

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Apneic Oxygenation High-flow Nasal Cannulae Bariatric Surgery Anesthesia Induction

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Consented patients will be randomly assigned either to the interventional group (High Flow Nasal Cannula- HFNC) or to the control group (CON). The Group HFNC will be preoxygenated using HFNC and the Group CON will receive standard preoxygenation.

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

HFNC (High Flow Nasal Cannulae)

High Flow Nasal Cannulae providing humidified, high-flow oxygen during induction of anesthesia

Group Type EXPERIMENTAL

HFNC

Intervention Type DEVICE

High flow nasal oxygen (60 l) under GA

CON (control)

Standard flow oxygen during induction of anesthesia

Group Type ACTIVE_COMPARATOR

CON (control)

Intervention Type DEVICE

Standard oxygen (10-15 l) under GA

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

HFNC

High flow nasal oxygen (60 l) under GA

Intervention Type DEVICE

CON (control)

Standard oxygen (10-15 l) under GA

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age more than18 years old
* ASA status I-III
* Elective surgery performed under general anesthesia requiring endotracheal intubation
* BMI more than 40 kg/m2

Exclusion Criteria

* Chronic respiratory disease
* SpO2 \<98% after supplementing oxygen
* Previous or anticipated difficult intubation
* Uncontrolled hypertension
* Ischemic heart disease
* Congestive heart failure
* Increased intracranial pressure
* Uncontrolled GERD
* Known allergy or contraindication to anesthesia drugs
* Nasal blockade contraindicating the use of HFNC

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No