Flexible Catheter for Insulin in Diabetes

NCT ID: NCT03182569

Last Updated: 2018-04-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-12-11

Study Completion Date

2018-04-09

Brief Summary

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Use of a flexible subcutaneous catheter improves comfort in patients with DKA compared to the usual treatment with a metal needle.

Detailed Description

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Assess whether the use of a flexible subcutaneous catheter improves comfort in patients with DKA compared to the usual treatment with a metal needle.

Compare the metabolic evolution of patients with DKA using a flexible subcutaneous catheter for insulin administration vs. a metal needle.

Conditions

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Diabetic Ketoacidosis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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flexible catheter

The flexible Subcutaneous catheter for insulin administration

Group Type EXPERIMENTAL

FLEXIBLE CATHETER

Intervention Type DEVICE

hourly rigid needle puncture

Hourly rigid needle puncture for Subcutaneous insulin administration

Group Type ACTIVE_COMPARATOR

hourly rigid needle puncture

Intervention Type DEVICE

Interventions

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FLEXIBLE CATHETER

Intervention Type DEVICE

hourly rigid needle puncture

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 5 to 18 years, admitted with diagnoses of DKA. DKA is defined when patients meets all the following biochemical baseline criteria (before initial hydration):
* Glucose\> 200 mg / dl
* pH \< 7.3
* Bicarbonate \< 15mmol/l.

Exclusion Criteria

* Patients referred from another institution with a different treatment, and those who requires intensive care on admission.
Minimum Eligible Age

5 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital General de Niños Pedro de Elizalde

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Laura Beaudoin, MD

Role: PRINCIPAL_INVESTIGATOR

Hospital General de Niños Pedro de Elizalde

Locations

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Hospital General de Niños Pedro de Elizalde

Buenos Aires, Constitucion, Argentina

Site Status

Countries

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Argentina

References

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Hanas R, Adolfsson P, Elfvin-Akesson K, Hammaren L, Ilvered R, Jansson I, Johansson C, Kroon M, Lindgren J, Lindh A, Ludvigsson J, Sigstrom L, Wiik A, Aman J. Indwelling catheters used from the onset of diabetes decrease injection pain and pre-injection anxiety. J Pediatr. 2002 Mar;140(3):315-20. doi: 10.1067/mpd.2002.122470.

Reference Type BACKGROUND
PMID: 11953729 (View on PubMed)

Beaudoin ML, Torrents M, Tittarelli MF, Hamui M, Ibarra M, Ferraro M, Ferreira JP. Use of a Flexible Catheter for the Administration of Subcutaneous Insulin in Diabetic Ketoacidosis: A Feasibility Controlled Clinical Trial. Hosp Pediatr. 2021 Apr;11(4):396-400. doi: 10.1542/hpeds.2020-0063. Epub 2021 Mar 9.

Reference Type DERIVED
PMID: 33687988 (View on PubMed)

Other Identifiers

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HGNPE-247-2016

Identifier Type: -

Identifier Source: org_study_id

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