Physiological Effect of Ataulfo Mango (Manguifera Indica) Beverage in Exercise

NCT ID: NCT03182543

Last Updated: 2017-06-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

19 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-01

Study Completion Date

2017-04-30

Brief Summary

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The aim of this study is to assess the antioxidant capacity of two mango base beverages (AM1, AM2), against exercise-induced oxidative stress.

Detailed Description

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Introduction. The post-consumption physiological effect of mango cv. "Ataulfo" pulp (MP) and peel (MC) in humans before exercise has been poorly evaluated.

Objective. To evaluate the physiological response, to consumption of two mango base beverages, AM1 (200g MP/ 600mL water) and AM2 (160g MP; 40g MC / 600mL water), before and after a submaximal exercise test.

Methods. The antioxidant profile and physicochemical characteristics of AM1 and AM2 were evaluated. Several cardiorespiratory, anthropometric and body composition parameters of 19 university students, prior to the consumption of AM1, AM2 and water, were evaluated in three non-consecutive sessions (self-control cases). The glycemic, lactic and antioxidant (FRAP), uric acid (AU), reduced glutathione (GSH) and lipid oxidation (TBARS) and protein carbonyls (PC) responses were evaluated in plasma before and after an incremental cycle ergometer exercise test.

Conditions

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Exercise-induced Oxidative Stress

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

The prescription of the treatments (AM1, AM2) and control (water) was randomized. The subject consumed 600mL of AM1, AM2 or water. 2 hours later subject performed the exercise test. Next treatment was evaluated after a week of wash-out.
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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AM1

Mango pulp beverage

Group Type EXPERIMENTAL

Mango pulp beverage

Intervention Type DIETARY_SUPPLEMENT

The subject consumes mango pulp beverage (200 g mango pulp + 600 mL water). 2 hours later subject performs the exercise test.

Washout: 1 week washout period prior to the administration of this intervention to avoid possible carryover effect.

AM2

Mango pulp and peel beverage

Group Type EXPERIMENTAL

Mango pulp and peel beverage

Intervention Type DIETARY_SUPPLEMENT

The subject consumes mango pulp and peel beverage (160 g mango pulp + 40 g mango peel + 600 mL water). 2 hours later subject performs the exercise test.

Washout: 1 week washout period prior to the administration of this intervention to avoid possible carryover effect.

Control

Control beverage

Group Type PLACEBO_COMPARATOR

Control beverage

Intervention Type DIETARY_SUPPLEMENT

The subject consumes control beverage (600 mL water). 2 hours later subject performs the exercise test.

Washout: 1 week washout period prior to the administration of this intervention to avoid possible carryover effect.

Interventions

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Mango pulp beverage

The subject consumes mango pulp beverage (200 g mango pulp + 600 mL water). 2 hours later subject performs the exercise test.

Washout: 1 week washout period prior to the administration of this intervention to avoid possible carryover effect.

Intervention Type DIETARY_SUPPLEMENT

Mango pulp and peel beverage

The subject consumes mango pulp and peel beverage (160 g mango pulp + 40 g mango peel + 600 mL water). 2 hours later subject performs the exercise test.

Washout: 1 week washout period prior to the administration of this intervention to avoid possible carryover effect.

Intervention Type DIETARY_SUPPLEMENT

Control beverage

The subject consumes control beverage (600 mL water). 2 hours later subject performs the exercise test.

Washout: 1 week washout period prior to the administration of this intervention to avoid possible carryover effect.

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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AM1 200 g mango pulp + 600 mL water AM2 160 g mango pulp + 40 g mango peel + 600 mL water 600 mL water

Eligibility Criteria

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Inclusion Criteria

* healthy male
* university student
* no alcohol, cigar or drugs consumption

Exclusion Criteria

* no antioxidant supplement or ergogenic consumption
* health issues with performing physical activity
Minimum Eligible Age

17 Years

Maximum Eligible Age

28 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Universidad Autonoma de Ciudad Juarez

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Abraham Wall-Medrano, PhD

Role: STUDY_DIRECTOR

Universidad Autónoma de Ciudad Juárez

Gregorio Chavez-Treviño, MS

Role: PRINCIPAL_INVESTIGATOR

Universidad Autónoma de Ciudad Juárez

References

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Alvarez-Parrilla E, De La Rosa LA, Legarreta P, Saenz L, Rodrigo-Garcia J, Gonzalez-Aguilar GA. Daily consumption of apple, pear and orange juice differently affects plasma lipids and antioxidant capacity of smoking and non-smoking adults. Int J Food Sci Nutr. 2010 Jun;61(4):369-80. doi: 10.3109/09637480903514041.

Reference Type BACKGROUND
PMID: 20109132 (View on PubMed)

Ramos-Jimenez A, Hernandez-Torres RP, Wall-Medrano A, Torres-Duran PV, Juarez-Oropeza MA, Solis Ceballos JA. Acute physiological response to indoor cycling with and without hydration; case and self-control study. Nutr Hosp. 2013 Sep-Oct;28(5):1487-93. doi: 10.3305/nh.2013.28.5.6698.

Reference Type BACKGROUND
PMID: 24160205 (View on PubMed)

Spirlandeli AL, Deminice R, Jordao AA. Plasma malondialdehyde as biomarker of lipid peroxidation: effects of acute exercise. Int J Sports Med. 2014 Jan;35(1):14-8. doi: 10.1055/s-0033-1345132. Epub 2013 Jun 14.

Reference Type BACKGROUND
PMID: 23771832 (View on PubMed)

Wang CY, Haskell WL, Farrell SW, Lamonte MJ, Blair SN, Curtin LR, Hughes JP, Burt VL. Cardiorespiratory fitness levels among US adults 20-49 years of age: findings from the 1999-2004 National Health and Nutrition Examination Survey. Am J Epidemiol. 2010 Feb 15;171(4):426-35. doi: 10.1093/aje/kwp412. Epub 2010 Jan 15.

Reference Type BACKGROUND
PMID: 20080809 (View on PubMed)

Wall-Medrano A, Olivas-Aguirre FJ, Velderrain-Rodriguez GR, Gonzalez-Aguilar A, de la Rosa LA, Lopez-Diaz JA, Alvarez-Parrilla E. [Mango: agroindustrial aspects, nutritional/functional value and health effects]. Nutr Hosp. 2014 Nov 1;31(1):67-75. doi: 10.3305/nh.2015.31.1.7701. Spanish.

Reference Type BACKGROUND
PMID: 25561099 (View on PubMed)

Other Identifiers

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UACJ-ICB-2017-01

Identifier Type: -

Identifier Source: org_study_id

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