Blood Flow Index as an Indicator of Successful Peripheral Nerve Block

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

110 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-05-27

Study Completion Date

2017-09-04

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Laser speckle contrast imaging (LSCI) allows real-time, non-invasive, quantitative measurements of regional blood flow. The aim of this prospective observational study was to evaluate the blood flow changes by LSCI after peripheral nerve block and determine whether this novel optical technique can be used as a reliable indicator of successful blocks.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Clinical Study of Treatment of Acute Spinal Cord Injury by Near Infrared Light Irradiation

NCT03643419

Spinal Cord Injuries Photobiology Neurological Rehabilitation +1 more

UNKNOWN NA

Orthostatic, Respiratory, Balance-Intervention

NCT04210063

Spinal Cord Injuries

COMPLETED NA

Comparison of Both Metabolic and Functional Effects Induced by Two Neuromuscular Electrical Stimulation Protocols: A Comprehensive Approach Using Magnetic Resonance Imaging and Spectroscopy

NCT02001675

Healthy

UNKNOWN NA

The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment Syndrome

NCT00921271

Compartment Syndrome

COMPLETED

Near-Infrared Imaging of Motor Imagery Effects in Spinal Cord Injury

NCT07106060

SCI - Spinal Cord Injury Motor Imagery Brain-Computer Interfaces

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Methods: One hundred adult patients scheduled for elective upper or lower limb surgery with peripheral nerve block will receive LSCI measurements and pinprick sensory tests before the block and at 5-min intervals till 30 min after the block. The sensitivity, specificity of LSCI as a diagnostic method will be determined by receiver operator characteristic analysis.

Clinical Implications: LSCI with quantitative data could be used as an indicator of successful blocks.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Laser

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Peripheral nerve block group

patients scheduled for elective upper or lower limb surgery with peripheral nerve block will receive LSCI measurements and pinprick sensory tests at 5 min before the block and at 5-min intervals till 30 min after the block.

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* informed consent
* American Society of Anesthesiologists physical statusⅠ-Ⅱ
* Undergo elective upper or lower limb surgery with peripheral nerve block

Exclusion Criteria

* refusal to participate in the study
* peripheral vascular disease
* digit injury or deficiency
* colored or infected fingernails/toenails
* BMI\>35
* those who had taken vasodilatory drugs before surgery
* preoperative analgesic medications
* Any contraindications to peripheral nerve block such as coagulation abnormalities, allergy to local anaesthetics, peripheral neuropathy.

Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No