Efficacy of Low Dose of Proton Pump Inhibitor in Treatment Bleeding Ulcers

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

295 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-31

Study Completion Date

2018-06-04

Brief Summary

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Determining the efficacy of low dose of PPI in management acute peptic ulcer bleeding

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Detailed Description

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Determining the efficacy of low dose meaning 40 mg of omeprazole twice in management acute peptic ulcer bleeding

Conditions

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Gastroduodenal Ulcer Marginal Ulcer Peptic Ulcer Hemorrhage

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Low Dose PPI

patients with upper upper gastrointestinal bleeding were treated in low dose of proton Bump inhibitor meaning 40 mg twice daily

Omeprazole 40 MG

Intervention Type DRUG

Omperazole 40 mg twice daily

Interventions

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Omeprazole 40 MG

Omperazole 40 mg twice daily

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

High risk ulcers defined according to the Forrest classification With respect to high-risk stigmata, active bleeding was defined as a continuous blood spurting (Forrest IA) oozing (Forrest IB) from the ulcer base. A non-bleeding visible vessel at endoscopy was defined as a discrete protuberance at the ulcer base(Forrest IIA).

An adherent clot was one that was resistant to forceful irrigation or suction (Forrest IIB).