Cardiac Remodeling and Prognosis in Secondar Tricuspid Regurgitation

NCT ID: NCT03159923

Last Updated: 2023-04-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-19

Study Completion Date

2023-03-23

Brief Summary

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The aim of this study is to improve the definition of the two main types of secondary tricuspid regurgitation.

Detailed Description

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Conditions

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Remodeling, Cardiac Tricuspid Regurgitation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Moderate to severe tricuspid regurgitation (≥ 2/4) diagnosed with echocardiography in patients stabilized.

Moderate to severe tricuspid regurgitation (≥ 2/4) diagnosed with echocardiography in patients stabilized.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Any patients ≥ 18 years old, with moderate to severe tricuspid regurgitation (≥ 2/4), agreeing to participate ;
* The patients included can be ambulatory patients or stabilized hospitalised patients (meaning patient clinicaly stable, not decompensated, and whose normovolemia has been checked).
* Non opposition of the patient

Exclusion Criteria

* Patient whose accoustic window is judged by the operator as incompatible with a precise evaluation of the tricuspid regurgitation or anatomy of the right cavity ;
* TR \< grade 2 ;
* TR secondary to primary pulmonary hypertension or congenital cardiopathy ;
* Primary tricuspid regurgitation (due to rheumatic heart disease, medication - included benfluorex, due to endocarditis, valvular prolapse, carcinoid syndrom or a cardiac stimulation lead …) ;
* Cardiopathy with significative systolic dysfunction (FE\< 40%) ;
* Patients whose life expectantcy is less than 1 year due to a pathology independent of the TR (neoplasic process for example) ;
* Patient under judicial protection.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rennes University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Erwan DONAL, PhD

Role: PRINCIPAL_INVESTIGATOR

Rennes University Hospital

Locations

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Chu Amiens-Picardie - Site Sud

Amiens, , France

Site Status

Ap-Hp - Hopital Henri Mondor

Créteil, , France

Site Status

CHU de DIJON - HOPITAL FRANCOIS MITTERAND

Dijon, , France

Site Status

Chu Grenoble - Michallon

Grenoble, , France

Site Status

Ghicl - Hopital Saint Philibert

Lomme, , France

Site Status

Chu Marseille - Hopital Nord

Marseille, , France

Site Status

Hôpital Saint Joseph

Marseille, , France

Site Status

Clinique Du Pont de Chaume

Montauban, , France

Site Status

CLINIQUE du MILLENAIRE

Montpellier, , France

Site Status

Chu de Nancy - Hopital de Brabois

Nancy, , France

Site Status

CHU de NANTES - HOTEL DIEU

Nantes, , France

Site Status

Ap-Hp - Hopital Saint-Antoine

Paris, , France

Site Status

Chu de Bordeaux - Groupe Hospitalier Sud

Pessac, , France

Site Status

CHU de Rennes

Rennes, , France

Site Status

CHU de TOULOUSE - HOPITAL RANGUEIL

Toulouse, , France

Site Status

Clinique NCT+

Tours, , France

Site Status

CHU de TOURS - HOPITAL TROUSSEAU

Tours, , France

Site Status

Countries

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France

Other Identifiers

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35RC16_8919_TRAP

Identifier Type: -

Identifier Source: org_study_id

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