Popliteal Plexus Block for Postoperative Pain After ACL Reconstruction

NCT ID: NCT03130049

Last Updated: 2018-01-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-27

Study Completion Date

2017-12-04

Brief Summary

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The study aims to investigate the effect of the popliteal plexus block (PPB) on postoperative pain in patients undergoing anterior cruciate ligament (ACL) reconstruction.

Detailed Description

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Postoperative pain following ACL reconstruction can be alleviated with an ultrasound-guided femoral triangle block (FTB). However, it is the investigators' observation that 10-20 % of the patients still complain of intense pain localized in the center of the knee.

Cadaver dissection studies have shown that an injection into the distal part of the adductor canal will spread to the popliteal fossa, and one dissection study showed consistent spread to the popliteal plexus.

The study team hypothesized that a PPB will reduce the postoperative pain, when it is used as a supplement to the FTB in patients undergoing ACL reconstruction.

Conditions

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Anterior Cruciate Ligament Injury Postoperative Pain

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Pilot study
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Patients with postoperative pain, NRS >3

Patients reporting postoperative pain (NRS \>3) localized to the center of the knee (10 patients) will receive a popliteal plexus block

Group Type EXPERIMENTAL

Popliteal plexus block

Intervention Type PROCEDURE

10 mL Marcain-adrenalin 5 mg/mL + 5 microgram/mL. Ultrasound-guided injection into the distal part of the adductor canal

Patients with postoperative pain, NRS ≤ 3

(approx. 90 patients)

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Popliteal plexus block

10 mL Marcain-adrenalin 5 mg/mL + 5 microgram/mL. Ultrasound-guided injection into the distal part of the adductor canal

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing ACL reconstruction on one of the two trial sites
* Age ≥ 18
* American Society of Anesthesiologists (ASA) status I-III
* Informed consent

Exclusion Criteria

* Patients unable to cooperate
* Patients not able to speak Danish or with other communication problems
* Pregnancy
* Contraindication towards any medical product used in the study
* Preoperatively reduced sensation on the medial and lateral part of the lower leg
* Patients with diabetes requiring medical treatment
* Preoperative intake of opioids (dosed \> once daily)
* ACL revision
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jan M Jensen, MD

Role: PRINCIPAL_INVESTIGATOR

Aarhus University Hospital

Christian Jessen, MD

Role: PRINCIPAL_INVESTIGATOR

The Regional Hospital in Horsens

Locations

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Aarhus University Hospital

Aarhus C, , Denmark

Site Status

The Regional Hospital in Horsens

Horsens, , Denmark

Site Status

Countries

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Denmark

References

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Wong WY, Bjorn S, Strid JM, Borglum J, Bendtsen TF. Defining the Location of the Adductor Canal Using Ultrasound. Reg Anesth Pain Med. 2017 Mar/Apr;42(2):241-245. doi: 10.1097/AAP.0000000000000539.

Reference Type BACKGROUND
PMID: 28002228 (View on PubMed)

Bendtsen TF, Moriggl B, Chan V, Borglum J. The Optimal Analgesic Block for Total Knee Arthroplasty. Reg Anesth Pain Med. 2016 Nov/Dec;41(6):711-719. doi: 10.1097/AAP.0000000000000485.

Reference Type BACKGROUND
PMID: 27685346 (View on PubMed)

Grevstad U, Mathiesen O, Valentiner LS, Jaeger P, Hilsted KL, Dahl JB. Effect of adductor canal block versus femoral nerve block on quadriceps strength, mobilization, and pain after total knee arthroplasty: a randomized, blinded study. Reg Anesth Pain Med. 2015 Jan-Feb;40(1):3-10. doi: 10.1097/AAP.0000000000000169.

Reference Type BACKGROUND
PMID: 25376972 (View on PubMed)

Goffin P, Lecoq JP, Ninane V, Brichant JF, Sala-Blanch X, Gautier PE, Bonnet P, Carlier A, Hadzic A. Interfascial Spread of Injectate After Adductor Canal Injection in Fresh Human Cadavers. Anesth Analg. 2016 Aug;123(2):501-3. doi: 10.1213/ANE.0000000000001441.

Reference Type BACKGROUND
PMID: 27442773 (View on PubMed)

Other Identifiers

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Protokol_PPB_ACL_21042017

Identifier Type: -

Identifier Source: org_study_id

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