Evaluation Of Clinical Results And Imaging Of Anterior Cruciate Ligament Reconstruction With Orthopure Xt

NCT ID: NCT06091488

Last Updated: 2025-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-12

Study Completion Date

2025-08-25

Brief Summary

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The purpose of this study is to evaluate subjective and objective clinical outcomes and imaging data of subjects undergoing reconstruction or revision of LCA reconstruction using OrthoPure XT

Detailed Description

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Conditions

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ACL ACL Injury

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Experimental

Patients with anterior cruciate ligament injury, in which the patient's own autologous tendons cannot be used, will be treated with the ligamentous reconstruction device.

Group Type EXPERIMENTAL

Orthopure

Intervention Type OTHER

Reconstruction of the anterior cruciate ligament of the knee in the patient.

Interventions

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Orthopure

Reconstruction of the anterior cruciate ligament of the knee in the patient.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients between the ages of 18 and 65 at the time of ACL reconstruction surgery;
* Patients aged 35 to 65 at the time of primary ACL reconstruction surgery;
* Male and female sex;
* First injury of the ACL with impossibility of use of autograft (patellar tendinopathy, quadriceps tendinopathy, goose leg tendinopathy) or refusal to use allograft (Bank tendon);
* Recurrence of ACL injury with impossibility of use of autograft (prior use/tendinopathy of the patellar, previous use/tendinopathy of the quadriceps, previous use/tendinopathy of the goose leg) or refusal to use allograft (tendon of Bank);

Exclusion Criteria

* Patients who do not consent to be included in the study
* Presence of haematological, rheumatic or haemorrhagic disease time of assessment
* ACL primary reconstruction in subjects under 35
* Allergies and/or reactions from hypersensitivity or religious objection to the use of porcine derivation
* Pregnant and/or breastfeeding women
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituto Ortopedico Rizzoli

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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IRCCS Istituto Ortopedico Rizzoli

Bologna, , Italy

Site Status

Countries

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Italy

References

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Collins JE, Katz JN, Donnell-Fink LA, Martin SD, Losina E. Cumulative incidence of ACL reconstruction after ACL injury in adults: role of age, sex, and race. Am J Sports Med. 2013 Mar;41(3):544-9. doi: 10.1177/0363546512472042. Epub 2013 Jan 9.

Reference Type RESULT
PMID: 23302260 (View on PubMed)

Kessler MA, Behrend H, Henz S, Stutz G, Rukavina A, Kuster MS. Function, osteoarthritis and activity after ACL-rupture: 11 years follow-up results of conservative versus reconstructive treatment. Knee Surg Sports Traumatol Arthrosc. 2008 May;16(5):442-8. doi: 10.1007/s00167-008-0498-x.

Reference Type RESULT
PMID: 18292988 (View on PubMed)

Costa GG, Grassi A, Perelli S, Agro G, Bozzi F, Lo Presti M, Zaffagnini S. Age over 50 years is not a contraindication for anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc. 2019 Nov;27(11):3679-3691. doi: 10.1007/s00167-019-05450-1. Epub 2019 Apr 3.

Reference Type RESULT
PMID: 30944945 (View on PubMed)

Other Identifiers

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ACL-PURE

Identifier Type: -

Identifier Source: org_study_id

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