Effectiveness of Tai Chi Training on Metabolic Syndrome

NCT ID: NCT03107741

Last Updated: 2020-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

543 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-02-29

Study Completion Date

2019-02-28

Brief Summary

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Metabolic syndrome (MetS) is a serious public health problem in Hong Kong and worldwide. Older adults, the age group with the highest prevalence of MetS, may prefer specific exercise modalities that are suitable for their regular participation to manage MetS. This project aims to evaluate the effectiveness of Tai Chi, a very suitable exercise for older adults, to alleviate MetS in older population

Detailed Description

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PURPOSE/OBJECTIVE: Metabolic syndrome (MetS) is a serious public health problem in Hong Kong and worldwide. Older adults, the age by specific exercise modalities that are suitable for regular participation. This project aims to evaluate the effectiveness of Tai Chi to alleviate MetS in older population.

DESIGN \& METHODS: This study is a three-arm assesscer blinded randomized controlled trial. Older adults aged 50 years or above with abdominal obesity will be randomly assigned to passive control, active control and Tai Chi groups. Subjects assigned to Tai Chi and active control groups will receive a 12-week intervention of Tai Chi and generic fitness, respectively. No intervention will be given to the passive control group. Outcome measures including waist circumference, blood pressure, blood glucose, triglyceride and high density lipoprotein-cholesterol will be assessed at baseline, post-intervention and follow-up (6 months after the end of intervention) assessments in all groups.

HYPOTHESES: We hypothesize that: 1) improvements of waist circumference and other indicators of MetS are found in Tai Chi group but not in passive control group and 2) improvements of waist circumference and other indicators of MetS are more profound in Tai Chi group than active control group.

Conditions

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Metabolic Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Passive Control

Subjects in this group will not receive any intervention.

Group Type NO_INTERVENTION

No interventions assigned to this group

Conventional Exercise

Subjects in this group will receive three 1-hour conventional exercise training sections per week for 12 weeks

Group Type PLACEBO_COMPARATOR

Conventional Exercise

Intervention Type OTHER

Subjects in this group will receive three 1-hour conventional exercise training sections per week for 12 weeks

Tai Chi

Subjects in this group will receive three 1-hour tai chi training sections per week for 12 weeks

Group Type ACTIVE_COMPARATOR

Tai Chi

Intervention Type OTHER

Subjects in this group will receive three 1-hour tai chi training sections per week for 12 weeks

Interventions

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Conventional Exercise

Subjects in this group will receive three 1-hour conventional exercise training sections per week for 12 weeks

Intervention Type OTHER

Tai Chi

Subjects in this group will receive three 1-hour tai chi training sections per week for 12 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Ethnic Chinese
* Abdominal Obese: Meeting the defined criteria of International Diabetes Federation (IDF) and National Cholesterol Education Program (NCEP) for abdominal obesity using Asian-specific cut off (waist circumference ≥ 90 cm for male; ≥ 80 cm for female)

Exclusion Criteria

* Regularly practice moderate-intensity exercise or tai chi (\>3 times a week of \>30-min/ session)
* Serious medical and somatic condition that prevent participation in generic fitness/Tai Chi exercise
* Serious chronic diseases known to affect mobility (eg. Neurological diseases, musculoskeletal disorder and autoimmune diseases)
* Under treatment for serious chronic diseases (eg. Cancer treatment)
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Angus Yu

OTHER

Sponsor Role lead

Responsible Party

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Angus Yu

Research Assistant

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Parco MF Siu, PhD

Role: PRINCIPAL_INVESTIGATOR

The University of Hong Kong

Locations

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The Hong Kong Polytechnic University

Hong Kong, , Hong Kong

Site Status

The University of Hong Kong

Hong Kong, , Hong Kong

Site Status

Countries

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Hong Kong

References

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Siu PM, Yu AP, Chin EC, Yu DS, Hui SS, Woo J, Fong DY, Wei GX, Irwin MR. Effects of Tai Chi or Conventional Exercise on Central Obesity in Middle-Aged and Older Adults : A Three-Group Randomized Controlled Trial. Ann Intern Med. 2021 Aug;174(8):1050-1057. doi: 10.7326/M20-7014. Epub 2021 Jun 1.

Reference Type DERIVED
PMID: 34058100 (View on PubMed)

Other Identifiers

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Tai Chi and Metabolic Syndrome

Identifier Type: -

Identifier Source: org_study_id

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