Molecular Analysis in Peritoneal Washing Citology for Locally Advanced Gastric Cancer

NCT ID: NCT03098758

Last Updated: 2019-07-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-05-08

Study Completion Date

2020-04-30

Brief Summary

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Gastric carcinoma is a disease with a high mortality. Peritoneal washing cytology has a recognized prognostic utility. However sensibility of this study is not appropriate. Studies with PCR (polymerase chain retrotranscription) can increase sensibility and accurate staging information.

Objective: To analyze the sensibility and specificity of the expression of CK20, CEA and Ber-EP4 with PCR technique in peritoneal washings of advanced gastric carcinoma without clinical evidence of peritoneal carcinomatosis.

Methodology: Retrotranscription analysis (RT-PCR) and quantitative PCR (qPCR) of CK20, CEA and Ber-EP4 in peritoneal washing. Test the feasibility of qPCR with this new marker (Ber-EP4). Comparison of the results with data obtained with conventional cytology. Study of peritoneal recurrence.

Detailed Description

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Conditions

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Gastric Cancer Polymerase Chain Reaction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients with resectable advanced gastric cancer
* Informed consent

Exclusion Criteria

* Macroscopic peritoneal carcinomatosis
* Non operable patients
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Corporacion Parc Tauli

OTHER

Sponsor Role lead

Responsible Party

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Alexis Luna

MD PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Alexis Luna, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Corporación Parc Taulí

Locations

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Parc Tauli Hospital Universitari

Sabadell, Barcelona, Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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Alexis Luna, MD PhD

Role: CONTACT

0034937231010 ext. 21458

Other Identifiers

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CIRPT_AL2017_1

Identifier Type: -

Identifier Source: org_study_id

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