Acute and Chronic Effects of Dynamic Apnea in Healthy Untrained Subjects

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-08

Study Completion Date

2017-11-20

Brief Summary

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The inclusion of short periods of apnea (several seconds) during exercise (i.e. dynamic apnea) induces a significant decrease in blood oxygenation and muscle tissue. To date, the immediate effects ("acute apnea") of this decrease in the quantity of oxygen available at the muscle and brain level are poorly understood. Moreover, a physical training during which these short periods of apnea ("chronic apnea") would be included could lead to physiological adaptations and to improvement in physical performance similar to those obtained during altitude training.

The purpose of this study is to evaluate the effects of acute dynamic apnea on metabolism.

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Detailed Description

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Conditions

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Apnea

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Apnea Group (GApn)

Program of training with exercises including apneas

Group Type EXPERIMENTAL

Program of training with exercises including apnea

Intervention Type OTHER

16 training session on cycle ergometry with exercises including apneas.

Control Group (GC)

Program of training with exercises without apnea

Group Type OTHER

Program of training with exercises without apnea

Intervention Type OTHER

16 training session on cycle ergometry with exercises without apnea

Interventions

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Program of training with exercises including apnea

16 training session on cycle ergometry with exercises including apneas.

Intervention Type OTHER

Program of training with exercises without apnea

16 training session on cycle ergometry with exercises without apnea

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* The cutaneous thickness at the vastus lateralis level lower than 1.5 cm to obtain the reliable muscle oxygenation measurement
* Subjects will have to sign the inform consent before the beginning of the study

Exclusion Criteria

* Contraindications to regular physical exercise practice
* To practice an endurance sport more than 1h/week
* Regular practice of apnea
* Chronic use of cannabis and/or alcohol
* Cardiac or metabolic pathology
* Asthma and/or bronchodilatator treatment
* ECG abnormality at rest
* Regular consumption of tobacco

Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes