Psychomotor Therapy for Very Premature Infants

NCT ID: NCT03093337

Last Updated: 2023-05-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

162 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-12-01

Study Completion Date

2017-07-08

Brief Summary

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Our current reflexion is that sensory dys-stimulations, including vestibule-proprioceptive disorders and unbalanced between brain and brainstem maturation of the neonatal period involve an early deviant development for immature infants that will be cascaded through the brain scaffolding and later development. The primary purpose is to determine whether the Early Psychomotor Therapy Intervention Program improves development and behavior in very preterm infants (VPI) at 24-month corrected age (CA).

Detailed Description

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VPI \< 30 week of amenorrhea were randomized, in a simple blind controlled trial. The psychomotor development was evaluated according to the Bayley Scales of Infant Development-III (BSID-III) at 2 years CA. An intermediate point was provided at 9 months CA. Pediatric standardized assessments and psychologist semi-directive interviews were conducted. Parents also completed a self-administering questionnaire relating to the post-traumatic stress. The intervention consisted on 20 therapy sessions between 2 and 9 months CA, in order to support infants' development, and parent-infant interactions and adjustment.

Extended description of the protocol, including more technical information (as compared to the Brief Summary) if desired. Do not include the entire protocol; do not duplicate information recorded in other data elements, such as eligibility criteria or outcome measures.

Conditions

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Premature Infant

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Psychomotor therapy

Early post hospital discharge psychomotor therapy.

Group Type EXPERIMENTAL

Early post hospital discharge psychomotor therapy

Intervention Type OTHER

The intervention consisted on 20 psychomotor therapy sessions between 2 and 9 months, in order to support infants' development, and parent-infant interactions and adjustment. The therapy was based on body and emotional positive feelings and experiences, leading to improve sensory motor and perceptive integration, interactive and exploratory behaviors, physiological and tonic-emotional self-regulation, motor organization and early coordination. The intervention was a partnership with the parents, leading to decode the baby needs and expectations, for the parents to experiment more positive feelings, to become more confident in their own skills and more sensitive, and in synchrony with their baby. Intervention was supported by a detailed assessment scale implemented in the regional network related to the follow-up for vulnerable babies.

Control

No specific support.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Early post hospital discharge psychomotor therapy

The intervention consisted on 20 psychomotor therapy sessions between 2 and 9 months, in order to support infants' development, and parent-infant interactions and adjustment. The therapy was based on body and emotional positive feelings and experiences, leading to improve sensory motor and perceptive integration, interactive and exploratory behaviors, physiological and tonic-emotional self-regulation, motor organization and early coordination. The intervention was a partnership with the parents, leading to decode the baby needs and expectations, for the parents to experiment more positive feelings, to become more confident in their own skills and more sensitive, and in synchrony with their baby. Intervention was supported by a detailed assessment scale implemented in the regional network related to the follow-up for vulnerable babies.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Infants with a gestational age between 24 and 30 weeks.

Exclusion Criteria

* Infants with congenital disease,
* Infants with brain bleeding grade III-IV,
* Infants with periventricular leucomalacia,
* Infants whose mothers had a documented history of physical or mental illness, or drug abuse
* Infants from non-French -speaking families.
Minimum Eligible Age

24 Weeks

Maximum Eligible Age

30 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Toulouse

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Corinne Alberge, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpital des enfants, Toulouse

Locations

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CH Albi

Albi, Midi-Pyrénées, France

Site Status

CH Auch

Auch, Midi-Pyrénées, France

Site Status

CH Cahors

Cahors, Midi-Pyrénées, France

Site Status

CH Castres

Castres, Midi-Pyrénées, France

Site Status

CHIVA centre hospitalier du val d'Ariège

Foix, Midi-Pyrénées, France

Site Status

CH Montauban

Montauban, Midi-Pyrénées, France

Site Status

CH Tarbes

Tarbes, Midi-Pyrénées, France

Site Status

Hôpital des enfants

Toulouse, Midi-Pyrénées, France

Site Status

Clinique Sarrus Teinturiers

Toulouse, Midi-Pyrénées, France

Site Status

Clinique Ambroise Paré

Toulouse, Midi-Pyrénées, France

Site Status

Countries

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France

References

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Shevell MI, Bodensteiner JB. Cerebral palsy: defining the problem. Semin Pediatr Neurol. 2004 Mar;11(1):2-4. doi: 10.1016/j.spen.2004.01.001.

Reference Type BACKGROUND
PMID: 15132247 (View on PubMed)

Hagberg B, Hagberg G, Beckung E, Uvebrant P. Changing panorama of cerebral palsy in Sweden. VIII. Prevalence and origin in the birth year period 1991-94. Acta Paediatr. 2001 Mar;90(3):271-7.

Reference Type BACKGROUND
PMID: 11332166 (View on PubMed)

Nelson KB. Can we prevent cerebral palsy? N Engl J Med. 2003 Oct 30;349(18):1765-9. doi: 10.1056/NEJMsb035364. No abstract available.

Reference Type BACKGROUND
PMID: 14585946 (View on PubMed)

Jacobsson B, Hagberg G. Antenatal risk factors for cerebral palsy. Best Pract Res Clin Obstet Gynaecol. 2004 Jun;18(3):425-36. doi: 10.1016/j.bpobgyn.2004.02.011.

Reference Type BACKGROUND
PMID: 15183137 (View on PubMed)

Palisano R, Rosenbaum P, Walter S, Russell D, Wood E, Galuppi B. Development and reliability of a system to classify gross motor function in children with cerebral palsy. Dev Med Child Neurol. 1997 Apr;39(4):214-23. doi: 10.1111/j.1469-8749.1997.tb07414.x.

Reference Type BACKGROUND
PMID: 9183258 (View on PubMed)

Weisglas-Kuperus N, Koot HM, Baerts W, Fetter WP, Sauer PJ. Behaviour problems of very low-birthweight children. Dev Med Child Neurol. 1993 May;35(5):406-16.

Reference Type BACKGROUND
PMID: 7684346 (View on PubMed)

Alberge C, Ehlinger V, Noack N, Bolzoni C, Colombie B, Breinig S, Dicky O, Delobel M, Arnaud C. Early psychomotor therapy in very preterm infants does not improve Bayley-III scales at 2 years. Acta Paediatr. 2023 Sep;112(9):1916-1925. doi: 10.1111/apa.16848. Epub 2023 Jun 5.

Reference Type RESULT
PMID: 37191836 (View on PubMed)

Other Identifiers

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07 227 01

Identifier Type: -

Identifier Source: org_study_id

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