The Effect of Surface Acoustic Waves on the Prevention of Colonization in Longterm Indwelling Urinary Caatheters

NCT ID: NCT03090373

Last Updated: 2017-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

63 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-01

Study Completion Date

2018-03-01

Brief Summary

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This is a double blinded rct to evaluate the effect of the UroShield SAW transducer on preventing bacterial colonization in longterm indwelling catheters. The duration of the trial is 30 days. The investigator will be quantifying the number of bacterial colonies in the urinary catheter and in the bladder in both the treatment and control group.

Detailed Description

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This is a double blinded Randomized controoled trial of 30 days duration. The trial device is the Uroshield, SAW device which is an externally applied device attached to the external portion of the urinary catheter.

Subjects will be randomized to a control group and the treatment group. The control group will receive standard of care for the care of indwelling urinary catheters, while being attached to a sham UroShield device. The treatment group will receive the same standard of care treatment but will be attached to an active UroShield SAW device.

At baseline and again at 30 days, both the catheter and retained urine from the bladder will be evaluated for the number of live colonies. These numbers will be evaluated to see if there is a difference between the active and sham devices.

Conditions

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Baacterial Colonization Urinary Tract Infections

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This is a double blinded, randomized controlled trial. All involved will be blinded as to whether the supplied UroShield device is active or a sham.
Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Investigators
The UroShield device actuator will activate and create the hum, which is the only sign of its working even in the active device. While the active device will transmit Surface Acoustic Waves, the sham device will work but will not transmit any acoustic waves.

Study Groups

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Control Group

At catheter replacement subjects will have a sham UroShield device attached to the external portion of the catheter and have it activated for 30 days.

Standard of care for the upkeep and cleanliness of the catheter will be adhered to.

At both the baseline and at the conclusion of 30 days, the distal end of the catheter will be collected as well as a sample of retained urine from the bladder and these samples will be evaluated for bacterial colonization.

Group Type SHAM_COMPARATOR

UroShield

Intervention Type DEVICE

The UroShield is an externally applied acoustic actuator which generates surface acoustic waves and transmits them along the length of the catheter. The device does not come in direct contact with the subjects.

Treatment Group

At catheter replacement subjects will have an active UroShield device attached to the external portion of the catheter and have it activated for 30 days.

Standard of care for the upkeep and cleanliness of the catheter will be adhered to.

At both the baseline and at the conclusion of 30 days, the distal end of the catheter will be collected as well as a sample of retained urine from the bladder and these samples will be evaluated for bacterial colonization.

Group Type ACTIVE_COMPARATOR

UroShield

Intervention Type DEVICE

The UroShield is an externally applied acoustic actuator which generates surface acoustic waves and transmits them along the length of the catheter. The device does not come in direct contact with the subjects.

Interventions

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UroShield

The UroShield is an externally applied acoustic actuator which generates surface acoustic waves and transmits them along the length of the catheter. The device does not come in direct contact with the subjects.

Intervention Type DEVICE

Other Intervention Names

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Surface Acoustic Wave Actuator

Eligibility Criteria

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Inclusion Criteria

* Currently being treated with an indwelling urinary catheter for at least 30 days.
* Ability to sign informed consent or have someone authorized to sign informed consent.

Exclusion Criteria

* Currently being treated for an active Urinary Tract infection.
* Previous treatment with Surface Acoustic Waves.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Nanovibronix

INDUSTRY

Sponsor Role collaborator

Rosenblum, Jonathan I., DPM

INDIV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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NanoVibronix

Elmsford, New York, United States

Site Status

Countries

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United States

Other Identifiers

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US-2

Identifier Type: -

Identifier Source: org_study_id

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