Postoperative Temperature Monitoring In Brain Trauma

NCT ID: NCT03068143

Last Updated: 2017-03-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-03-31

Study Completion Date

2018-02-28

Brief Summary

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This prospective observational study is designed to investigate the relationship between brain temperature, axillary temperature, rectal temperature, and bladder temperature of postoperative patients with brain trauma, and the relationship between brain temperature and prognosis. This study is conducted based on the following important assumptions. First, brain temperature of postoperative patients with brain trauma should be higher than the axillary temperature, rectal temperature and bladder temperature. Second, the consistency of brain temperature and bladder temperature is better than the consistency of brain temperature and axillary temperature, as well as that of brain temperature and rectal temperature. Third, brain temperature can help clinicians to predict the prognosis of patients with brain trauma. Therefore, brain temperature monitoring is significant in postoperative intensive care and treatment of patients with brain trauma.

Detailed Description

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Conditions

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Brain Injuries, Traumatic Body Temperature Changes

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Clinical or radiological diagnosis is brain trauma;
* The patient has surgical indications, and the patient or his/her family are willing to undergo operation including brain temperature monitoring probe implantation;
* Informed consent is obtained from the patient's family.

Exclusion Criteria

* At the time of admission there are serious systemic diseases, including severe infections, immune system diseases, blood system diseases, infectious diseases, severe liver and kidney dysfunction, malignant tumors, etc;
* Pregnant or lactating women;
* There are other brain tumors or cerebrovascular disease in the brain at the same time;
* There is a history of drug or alcohol abuse;
* Within 3 months before admission, live vaccines were inoculated.
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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RenJi Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Neurosurgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Guoyi Gao, Dr.

Role: CONTACT

+86-021-68383709

Facility Contacts

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Guoyi Gao, Dr.

Role: primary

+86-021-68383709

References

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Hayward JN, Baker MA. A comparative study of the role of the cerebral arterial blood in the regulation of brain temperature in five mammals. Brain Res. 1969 Dec;16(2):417-40. doi: 10.1016/0006-8993(69)90236-4. No abstract available.

Reference Type BACKGROUND
PMID: 4311724 (View on PubMed)

Mellergard P, Nordstrom CH. Intracerebral temperature in neurosurgical patients. Neurosurgery. 1991 May;28(5):709-13.

Reference Type BACKGROUND
PMID: 1876249 (View on PubMed)

Mellergard P, Nordstrom CH, Messeter K. Human brain temperature during anesthesia for intracranial operations. J Neurosurg Anesthesiol. 1992 Apr;4(2):85-91. doi: 10.1097/00008506-199204000-00003.

Reference Type BACKGROUND
PMID: 15815447 (View on PubMed)

Hirashima Y, Takaba M, Endo S, Hayashi N, Yamashita K, Takaku A. Intracerebral temperature in patients with hydrocephalus of varying aetiology. J Neurol Neurosurg Psychiatry. 1998 Jun;64(6):792-4. doi: 10.1136/jnnp.64.6.792.

Reference Type BACKGROUND
PMID: 9647313 (View on PubMed)

Camboni D, Philipp A, Schebesch KM, Schmid C. Accuracy of core temperature measurement in deep hypothermic circulatory arrest. Interact Cardiovasc Thorac Surg. 2008 Oct;7(5):922-4. doi: 10.1510/icvts.2008.181974. Epub 2008 Jul 25.

Reference Type BACKGROUND
PMID: 18658167 (View on PubMed)

Henker RA, Brown SD, Marion DW. Comparison of brain temperature with bladder and rectal temperatures in adults with severe head injury. Neurosurgery. 1998 May;42(5):1071-5. doi: 10.1097/00006123-199805000-00071.

Reference Type BACKGROUND
PMID: 9588552 (View on PubMed)

Weng WJ, Yang C, Huang XJ, Zhang YM, Liu JF, Yao JM, Zhang ZH, Wu XS, Mei T, Zhang CD, Jia J, Shi XF, Mao Q, Feng JF, Gao GY, Jiang JY. Effects of Brain Temperature on the Outcome of Patients with Traumatic Brain Injury: A Prospective Observational Study. J Neurotrauma. 2019 Apr 1;36(7):1168-1174. doi: 10.1089/neu.2018.5881. Epub 2018 Oct 10.

Reference Type DERIVED
PMID: 30215286 (View on PubMed)

Other Identifiers

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BT-201607

Identifier Type: -

Identifier Source: org_study_id

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