Serum Lactate in Convulsive Syncopes Compared to Non-convulsive Syncopes
NCT ID: NCT03062683
Last Updated: 2017-03-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2017-01-01
2017-12-31
Brief Summary
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Detailed Description
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So in the present prospective study, the serum lactate concentrations are compared following convulsive and non-convulsive syncopes.
The examinations are carried out in cardiological patients who receive a tipping table examination with the aim of initiating a syncope. The question is whether there is hyperlactatemia following convulsive syncopes. If no elevated serum lactate values were measured after convulsive syncopes, this would additionally indicate the great benefit of the serum lactate value as a diagnostic marker in the generalized epileptic seizure.
In addition, a comparison is made with the parameters creatine kinase, prolactin, pH-value, bicarbonate, sodium and potassium.
If increased serum lactate values are measured following a syncope further venous blood controls are carried out at intervals of 20 minutes within the first hour and then after 90 minutes and 120 minutes until normalization.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Non-convulsive syncope patients
Patients with a non-convulsive syncope triggered by a tilting table examination and whose serum lactate, prolactin and creatine kinase conc. in blood samples had been measured after the event.
Lactate, prolactin and creatine kinase conc.
Lactate, prolactin and creatine kinase conc. in blood samples were measured
Convulsive syncope patients
Patients with a convulsive syncope triggered by a tilting table examination and whose serum lactate, prolactin and creatine kinase conc. in blood samples had been measured after the event.
Lactate, prolactin and creatine kinase conc.
Lactate, prolactin and creatine kinase conc. in blood samples were measured
Interventions
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Lactate, prolactin and creatine kinase conc.
Lactate, prolactin and creatine kinase conc. in blood samples were measured
Eligibility Criteria
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Inclusion Criteria
* 18 years or older
Exclusion Criteria
* Age \< 18 years old
* Lack of capacity for consent
18 Years
ALL
No
Sponsors
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RWTH Aachen University
OTHER
Responsible Party
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Principal Investigators
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Oliver Matz, Dr.
Role: STUDY_DIRECTOR
RWTH Aachen University Hospital
Locations
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Department of Neurology/Department of Cardiology, University Hospital RWTH Aachen
Aachen, North Rhine-Westphalia, Germany
Countries
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Central Contacts
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Facility Contacts
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Manuel Dafotakis, Dr.
Role: backup
References
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Matz O, Zdebik C, Zechbauer S, Bundgens L, Litmathe J, Willmes K, Schulz JB, Dafotakis M. Lactate as a diagnostic marker in transient loss of consciousness. Seizure. 2016 Aug;40:71-5. doi: 10.1016/j.seizure.2016.06.014. Epub 2016 Jun 23.
Other Identifiers
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Laktat-2017
Identifier Type: -
Identifier Source: org_study_id
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