Omitting GnRH-antagonist Dose on the Day of Ovulation Trigger

NCT ID: NCT03044756

Last Updated: 2017-02-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE2/PHASE3

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-01

Study Completion Date

2017-12-30

Brief Summary

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Omitting the GnRH antagonist on the day of the trigger can be cost effective and more convenient to the women. We will study the impact of omitting the antagonist dose in a prospective randomized trial

Detailed Description

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Conditions

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Pituitary Downregulation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized controlled study
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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-ve arm

The women who do not receive the GnRH antagonist dose on the day of triggering of ovulation (omitted GnRH antagonist arm)

Group Type EXPERIMENTAL

Omit Citrotide 0.25 dose on the day of triggering of ovulation

Intervention Type DRUG

Omit Citrotide 0.25 dose on the day of triggering of ovulation

+ve arm

The women who receive the routine dose of GnRH antagonist on the day of triggering of ovulation (the usual protocol)

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Omit Citrotide 0.25 dose on the day of triggering of ovulation

Omit Citrotide 0.25 dose on the day of triggering of ovulation

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* All antagonist cycle ivf who agree to participate

Exclusion Criteria

* expected poor responders.
Minimum Eligible Age

20 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Osama Saber Thabet Abdalmageed

Lecturer of OBGYN, Women Health Hospital, Assiut Univerisity

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Osama Abdalmageed

Asyut, Non-US/Non-Canadian, Egypt

Site Status RECRUITING

Osama Abdalmageed

Asyut, Non-US/Non-Canadian, Egypt

Site Status RECRUITING

Countries

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Egypt

Facility Contacts

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Osama Abdalmageed

Role: primary

1007972027

Osama Abdalmageed

Role: primary

References

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Chang HJ, Lee JR, Jee BC, Suh CS, Lee WD, Kim SH. Cessation of gonadotropin-releasing hormone antagonist on triggering day in flexible multiple-dose protocol: A randomized controlled study. Clin Exp Reprod Med. 2013 Jun;40(2):83-9. doi: 10.5653/cerm.2013.40.2.83. Epub 2013 Jun 30.

Reference Type BACKGROUND
PMID: 23875164 (View on PubMed)

Other Identifiers

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Omit

Identifier Type: -

Identifier Source: org_study_id

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