The Effect of Oxytocin on the Acquisition and Consolidation of Trauma-Associated Memories

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

220 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-15

Study Completion Date

2018-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of the study is to examine whether oxytocin and oxytocin receptor gene polymorphism affect the development of intrusive memories, a cardinal symptom of PTSD.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Effect of Oxytocin on the Consolidation of Trauma-Associated Memories

NCT03875391

Intrusive Memories PTSD

COMPLETED NA

Prolonged Exposure and Oxytocin

NCT03238924

PTSD

COMPLETED PHASE2

Study of the Effects of Oxytocin on Attentional Bias and Startle in PTSD

NCT03211013

Posttraumatic Stress Disorder

COMPLETED EARLY_PHASE1

The Effect of Oxytocin on Fear Memory Consolidation Novel Intervention to Prevent Posttraumatic Stress Disorder (PTSD)

NCT01466127

Posttraumatic Stress Disorder

COMPLETED NA

The Efficacy of a Single Dose of Intranasal Oxytocin in the Prevention of Post Traumatic Stress Disorder (PTSD)

NCT01039766

Stress Disorders, Post-Traumatic

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Intrusive Memories

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Oxytocin and trauma film paradigm

Group Type EXPERIMENTAL

Oxytocin nasal spray

Intervention Type DRUG

Placebo and trauma film paradigm

Group Type PLACEBO_COMPARATOR

Placebos

Intervention Type DRUG

Placebo nasal spray

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Oxytocin nasal spray

Intervention Type DRUG

Placebos

Placebo nasal spray

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* healthy female volunteers
* German on a native level

Exclusion Criteria

* former or present disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5)
* any physical illnesses
* any medication intake (except oral contraceptive)
* history of traumatic experience, e.g. history of sexual abuse or rape
* pregnancy or lactation period
* follicular phase of menstrual cycle for all women not using oral contraceptives

Minimum Eligible Age

18 Years

Maximum Eligible Age

44 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes