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Effects of Ginger on Muscle Soreness and Dysfunction Stemming From Downhill Running

NCT ID: NCT03028454

Last Updated: 2017-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-31

Study Completion Date

2017-06-30

Brief Summary

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The objective of the study is to determine whether five days of ginger (Zingiber officinale) supplementation is effective at reducing muscle soreness and improving muscle function following downhill running. Long-distance running is often associated with acute muscle pain, swelling, and reduced muscle functioning, and consequently, many runners utilize non-steroidal anti-inflammatory drugs (NSAID). NSAID use is associated with gastrointestinal side-effects such as stomach discomfort, nausea, dyspepsia, asymptomatic ulcers, and symptomatic ulcers that, although rare, can be fatal. Ginger is a botanical compound that is Generally Recognized as Safe by the Food and Drug Administration (FDA). Evidence from osteoarthritis, dysmenorrhea, and resistance-training models indicate that ginger is effective at reducing general pain and muscle soreness. Therefore, this study will supplement 60 runners with roughly 1.5 g/day of ginger root or a placebo for 2 days prior to, the day of, and 2 days after downhill running. Participants will be evaluated for muscle soreness and function before and after the downhill run.

Detailed Description

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Conditions

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Muscle Soreness

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Ginger Root Capsule

Group Type EXPERIMENTAL

Ginger Root

Intervention Type DIETARY_SUPPLEMENT

Capsules containing 250 mg of ginger root extract standardized to contain at least 5% gingerol compounds, as well as an additional 225 mg of regular ginger root.

Placebo Capsule

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DIETARY_SUPPLEMENT

Capsules containing rice flour powder.

Interventions

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Ginger Root

Capsules containing 250 mg of ginger root extract standardized to contain at least 5% gingerol compounds, as well as an additional 225 mg of regular ginger root.

Intervention Type DIETARY_SUPPLEMENT

Placebo

Capsules containing rice flour powder.

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Be currently running ≥10 miles per week
* Have completed at least one run \>40 minutes over the past month

Exclusion Criteria

* Have no allergies to ginger
* Willing to avoid pain-relieving medications for the duration of the study
* Have no history of bleeding disorders nor currently taking blood thinners
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Old Dominion University

OTHER

Sponsor Role lead

Responsible Party

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Patrick Wilson, PhD

Assistant Professor of Exercise Science

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Human Performance Laboratory

Norfolk, Virginia, United States

Site Status

Countries

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United States

Other Identifiers

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934537-3

Identifier Type: -

Identifier Source: org_study_id