Diaphragmatic Activity During Weaning With NAVA, a Pilot Study (NAVA: Neurally Adjusted Ventilatory Assist)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-06-30

Study Completion Date

2013-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to describe the diaphragm electromyographic activity (Edi) in healthy lung patients due to obtain a reference to guide the weaning in those patients

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Neurally Adjusted Ventilatory Assist (NAVA) Study in Adults With Acute Respiratory Failure

NCT01730794

Acute Respiratory Failure

COMPLETED NA

Electrical Activity of the Diaphragm and Respiratory Mechanics During NAVA

NCT05689476

Work of Breathing Lung Transplantation Neurally Adjusted Ventilatory Assist +2 more

RECRUITING NA

Effect of NAVA on Weaning Duration in Difficult to Wean Patients

NCT01280773

Weaning

COMPLETED NA

Non-invasive Neurally Adjusted Ventilatory Assist in Healthy Volunteers

NCT00941044

Healthy

COMPLETED PHASE1

Estimation of the Diaphragm Electrical Activity and Intercostal Thickening Fraction During Different Pattern of Mechanical Ventilation: PSV Versus NAVA

NCT05990348

Respiratory Failure Weaning Failure

RECRUITING

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

We obtained the Edi recording data at each NAVA level during the weaning in NAVA group, and we compared the respiratory parameters between the PSV and NAVA groups

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Postoperative Patients

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

NAVA group with a specific catheter

The patients were allocated in the NAVA weaning protocol group

Group Type OTHER

weaning protocol

Intervention Type PROCEDURE

The patients were allocated in the NAVA weaning protocol group o in the PSV weaning protocol group

PSV group without a specific catheter

The patients were allocated in the PSV (pressure-support ventilation) weaning protocol group

Group Type OTHER

weaning protocol

Intervention Type PROCEDURE

The patients were allocated in the NAVA weaning protocol group o in the PSV weaning protocol group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

weaning protocol

The patients were allocated in the NAVA weaning protocol group o in the PSV weaning protocol group

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients who were scheduled for elective major surgery in which admission to the CCU (critical care unit) for postoperative care and short-term mechanical ventilation with rapid weaning were anticipated.

Exclusion Criteria

* Preoperative altered central nervous system, neuromuscular or lung disease and ASA (american society of anesthesiologists) classification group IV or NYHA (New York heart association) class IV in the case of cardiac patients. At the CCU, before randomisation, we also excluded patients requiring reoperation, and those who exhibited significant postsurgical bleeding, the development of myocardial infarction, and hemodynamic instability.

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No