Effect of Red Meat Intake on Occurrence of Serum Non-transferrin Bound Iron (NTBI)
NCT ID: NCT03019393
Last Updated: 2017-01-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
15 participants
INTERVENTIONAL
2016-05-31
2017-03-31
Brief Summary
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Detailed Description
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NTBI concentration before and after meal consumption will be compared.
Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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Beef
Beef topside fully cooked, 200g
Beef
200 g beef topside which is fully cooked will be provided to participant after overnight fast. The intervention is one time only.
Interventions
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Beef
200 g beef topside which is fully cooked will be provided to participant after overnight fast. The intervention is one time only.
Eligibility Criteria
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Inclusion Criteria
* C-reactive protein (CRP) \< 5 mg/L
Exclusion Criteria
* Regular intake of iron and other nutrient supplements within the past 4 months
* Regular intake of medication except oral contraceptives
* Acute or recent inflammatory or infectious symptoms
* Chronic gastrointestinal disorders or metabolic diseases
* Smoking
* Coeliac disease or gluten-related disorders
* Iron deficiency anemia (Hb \< 14 g/dL for males) with serum ferritin concentration \< 30 ng/mL)
* Non-iron deficiency anemia (serum ferritin concentration within normal range (30 - 300 ng/mL for males) but low hemoglobin (\< 14 g/dL for males)
* Iron overload conditions (serum ferritin concentration \> 300 ng/mL for males)
* Known hereditary disorders of iron metabolism
21 Years
45 Years
MALE
Yes
Sponsors
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Thomas Walczyk
OTHER
Responsible Party
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Thomas Walczyk
Associate Professor
Principal Investigators
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Thomas Walczyk, Ph.D
Role: PRINCIPAL_INVESTIGATOR
National University of Singapore
Locations
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National University of Singapore; National University Hospital
Singapore, , Singapore
Countries
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References
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Trumbo P, Yates AA, Schlicker S, Poos M. Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. J Am Diet Assoc. 2001 Mar;101(3):294-301. doi: 10.1016/S0002-8223(01)00078-5. No abstract available.
Monsen ER, Hallberg L, Layrisse M, Hegsted DM, Cook JD, Mertz W, Finch CA. Estimation of available dietary iron. Am J Clin Nutr. 1978 Jan;31(1):134-41. doi: 10.1093/ajcn/31.1.134.
Papanikolaou G, Pantopoulos K. Iron metabolism and toxicity. Toxicol Appl Pharmacol. 2005 Jan 15;202(2):199-211. doi: 10.1016/j.taap.2004.06.021.
Hutchinson C, Al-Ashgar W, Liu DY, Hider RC, Powell JJ, Geissler CA. Oral ferrous sulphate leads to a marked increase in pro-oxidant nontransferrin-bound iron. Eur J Clin Invest. 2004 Nov;34(11):782-4. doi: 10.1111/j.1365-2362.2004.01416.x. No abstract available.
Schumann K, Kroll S, Romero-Abal ME, Georgiou NA, Marx JJ, Weiss G, Solomons NW. Impact of oral iron challenges on circulating non-transferrin-bound iron in healthy Guatemalan males. Ann Nutr Metab. 2012;60(2):98-107. doi: 10.1159/000336177. Epub 2012 Mar 6.
Other Identifiers
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13-441
Identifier Type: -
Identifier Source: org_study_id
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