Role of Deep Brain Stimulation on Social Cognition in Parkinsonian Patients

NCT ID: NCT03004573

Last Updated: 2020-02-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-03-14

Study Completion Date

2019-12-13

Brief Summary

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Parkinson's disease (PD) is usually responsible of cognitive and behavioral non-motor signs with a major impact on the quality of life. Social cognition is a complex system relying on emotion recognition (neurons mirror system, NMS), the theory of mind (with its two parts: emotional and cognitive), but also on the social and cultural environment and the personal history. The first step in this model is represented by the NMS, which seems to be altered in PD patients for both positive and negative emotions as shown in our preliminary study. The investigator purpose is to investigate the role of the treatment (levodopa and deep brain stimulation) on the functioning of the NMS.

Detailed Description

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Conditions

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Parkinson Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Deep brain stimulation

Group Type EXPERIMENTAL

Neuropsychological detailed tests with focus on social cognition

Intervention Type OTHER

MATTIS, MOCA, BREF, Light points test, PDQ39

Interventions

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Neuropsychological detailed tests with focus on social cognition

MATTIS, MOCA, BREF, Light points test, PDQ39

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Parkinson's disease with motor fluctuations and dyskinesias receiving deep-brain stimulation
* Social insurance

Exclusion Criteria

* No affiliation to the social insurance
* Patients under guardianship
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Teodor Danaila, MD

Role: PRINCIPAL_INVESTIGATOR

Hospices Civils de Lyon

Locations

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Service de Neurologie C Hôpital " Pierre Wertheimer "

Bron, , France

Site Status

Countries

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France

Other Identifiers

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2016-A00143-48

Identifier Type: OTHER

Identifier Source: secondary_id

69 HCL15_0760

Identifier Type: -

Identifier Source: org_study_id

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