Pupillary Diameter Under Different Concentrations of Propofol
NCT ID: NCT02998424
Last Updated: 2018-06-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2016-05-31
2016-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
DOUBLE
Study Groups
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Propofol 1 µg/ml
Patients received a propofol infusion at an effect-site concentration of 1 µg/ml at the beginning of induction of general anesthesia for elective surgery.
Pupillary diameter measurement after 10 minutes.
Propofol
Continuous infusion
Pupillary diameter measurement
Instantaneous measure
Propofol 2 µg/ml
Patients received a propofol infusion at an effect-site concentration of 2 µg/ml at the beginning of induction of general anesthesia for elective surgery.
Pupillary diameter measurement after 10 minutes.
Propofol
Continuous infusion
Pupillary diameter measurement
Instantaneous measure
Propofol 3 µg/ml
Patients received a propofol infusion at an effect-site concentration of 3 µg/ml at the beginning of induction of general anesthesia for elective surgery.
Pupillary diameter measurement after 10 minutes.
Propofol
Continuous infusion
Pupillary diameter measurement
Instantaneous measure
Interventions
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Propofol
Continuous infusion
Pupillary diameter measurement
Instantaneous measure
Eligibility Criteria
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Inclusion Criteria
* ASA I or II who is scheduled for elective surgery under general anesthesia
Exclusion Criteria
* chronic pain
* under medication that interferes with autonomic nervous system
* obesity
* patient requiering a rapid sequence induction
13 Years
50 Years
ALL
No
Sponsors
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Hôpital Armand Trousseau
OTHER
Responsible Party
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Pr Isabelle CONSTANT
Professor
Principal Investigators
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Isabelle Constant, MD-PHD
Role: STUDY_DIRECTOR
Hopital Armand Trousseau, Université Paris 6, Département d'anesthésie
Locations
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Departement d'anesthesie Hopital Armand Trousseau
Paris, , France
Countries
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References
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Sabourdin N, Meniolle F, Chemam S, Rigouzzo A, Hamza J, Louvet N, Constant I. Effect of Different Concentrations of Propofol Used as a Sole Anesthetic on Pupillary Diameter: A Randomized Trial. Anesth Analg. 2020 Aug;131(2):510-517. doi: 10.1213/ANE.0000000000004362.
Other Identifiers
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PD and propofol
Identifier Type: -
Identifier Source: org_study_id
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