Maternal Inflammatory Parameters Within Routine Treatment With Betamethasone

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

140 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-09-30

Study Completion Date

2017-05-31

Brief Summary

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It is the aim of this study to detect the effect of Betamethasone on the maternal inflammatory parameters C-reactive protein (CRP) and leukocytes of a pregnant woman under threat of preterm delivery, for example because of a cervical infection.

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Detailed Description

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BACKGROUND

Cortisone influences the maternal number of leukocytes and CRP of a pregnant woman. Because of that, it is difficult to know if the medical treatment of an infection was successful and accordingly if the diagnosis was justified.

METHODS

In this study, the blood results of 75 pregnant women under threat of preterm delivery (week of gestation 23+0 to 34+6), treated with Betamethasone will be analysed. 65 pregnant women without complications serve as control group.

Conditions

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Preterm Birth

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Case Group

75 woman between the age of 18 to 50 years, week of gestation 23+0 - 34+6, threatening preterm delivery, application of Betamethasone

No interventions assigned to this group

Control Group

65 woman between the age of 18 to 50 years, week of gestation 23+0 - 34+6, no threatening preterm delivery

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* week of gestation 23+0 until 34+6

Exclusion Criteria

* infectious diseases f.e. hepatitis B or C, HIV
* diseases of the thyroid gland

75 Patients facing preterm labour 65 Patients acting as a control group, without preterm labor

Minimum Eligible Age

18 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No