Patient Outcomes After Hospitalization in Acute Geriatric Unit

NCT ID: NCT02949635

Last Updated: 2020-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

3532 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-09-07

Study Completion Date

2018-12-31

Brief Summary

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Three events can be considered of major importance for patients after a hospitalization in an AGU: death, hospital readmission, and institutionalization. Current published data do not allow the clinician to simultaneously estimate the risk of hospital readmission, institutionalization and death of an older patient according to his/her characteristics and various complications that occurred during the hospitalization. However, clinicians often need to estimate these risks at hospital discharge to adapt their therapeutic choices, their proposals post-hospital care, and provide reliable and fair information to the patient and his relatives.

Estimating simultaneously the hazard for each of these three events can be complex. Indeed, a death event hinder the observation of re-hospitalization or institutionalization if death occurs before these events. The death should be considered a competing risk in these analyzes. Hospital readmission may modify the risk of death or institutionalization and should be considered as an intermediate factor for these event. This complexity cannot be accounted with classical statistical models, like logistic regression models.

The purpose of this study is to use more appropriate statistical models (multi-state models) to better estimate simultaneously the risks of hospital readmission, institutionalization, and death of a patient given after hospitalization in AGU, and to show that accuracy of these estimations can be improved by taking into account complications that occurred during the stay in AGU.

Detailed Description

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Conditions

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Geriatric Disorder

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age 75 years and over
* Hospitalized in Acute Geriatric Unit
* Covered by a health insurance

Exclusion Criteria

* Refusal to participate to the study, as expressed by the patient or his/her next of kin
Minimum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ministry of Health, France

OTHER_GOV

Sponsor Role collaborator

University Hospital, Lille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Baptiste Beuscart, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Lille

Locations

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CHU d'Amiens

Amiens, , France

Site Status

CH Beauvais

Beauvais, , France

Site Status

CHU Caen

Caen, , France

Site Status

Hôpital Cardiologique, CHRU

Lille, , France

Site Status

GHICL, Saint Philibert

Lomme, , France

Site Status

CH Saint Quentin

Saint-Quentin, , France

Site Status

Countries

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France

References

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Prod'homme C, Deschasse G, Visade F, Hennion C, Charpentier A, Gaxatte C, Bloch F, Delecluse C, Puisieux F, Beuscart JB. Palliative use of midazolam in acute geriatric units: a multicenter ambispective study. BMC Geriatr. 2025 Apr 10;25(1):241. doi: 10.1186/s12877-025-05860-6.

Reference Type DERIVED
PMID: 40211151 (View on PubMed)

Deschasse G, Charpentier A, Prod'homme C, Genin M, Delecluse C, Gaxatte C, Gerard C, Bukor Z, Devulder P, Couvreur LA, Bloch F, Puisieux F, Visade F, Beuscart JB. Transition to Comfort Care Only and End-of-Life Trajectories in an Acute Geriatric Unit: A Secondary Analysis of the DAMAGE Cohort. J Am Med Dir Assoc. 2022 Sep;23(9):1492-1498. doi: 10.1016/j.jamda.2022.04.016. Epub 2022 May 21.

Reference Type DERIVED
PMID: 35609637 (View on PubMed)

Deschasse G, Bloch F, Drumez E, Charpentier A, Visade F, Delecluse C, Loggia G, Lescure P, Attier-Zmudka J, Bloch J, Gaxatte C, Van Den Berghe W, Puisieux F, Beuscart JB. Development of a Predictive Score for Mortality at 3 and 12 Months After Discharge From an Acute Geriatric Unit as a Trigger for Advanced Care Planning. J Gerontol A Biol Sci Med Sci. 2022 Aug 12;77(8):1665-1672. doi: 10.1093/gerona/glab217.

Reference Type DERIVED
PMID: 34375411 (View on PubMed)

Other Identifiers

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2014-A01670-47

Identifier Type: OTHER

Identifier Source: secondary_id

API 13-19-002

Identifier Type: OTHER

Identifier Source: secondary_id

2014_23

Identifier Type: -

Identifier Source: org_study_id

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