Comparison of Two Calorie Restricted MediterrAsian Diet on Weight Loss in FTO rs9939609 Overweight Carriers
NCT ID: NCT02940197
Last Updated: 2019-04-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
145 participants
INTERVENTIONAL
2016-10-31
2019-03-31
Brief Summary
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Objective: we assess the effect of two different calorie restriction with MediterrAsian diet on weight loss of FTO rs9939609 carriers with overweight.
Methods: we recruit 80 healthy overweight participants aged 20-45 years that randomly allocated in two interventional group \[group 1: Mediterrasian diet according to adjusted ideal body weight with 500 calories restriction (RD) and group 2: without 500 calories restriction (NRD)+ Moderate physical activity\]. Anthropometric indices will be assesses for all participants weekly for two month. The criteria for weight loss is 250-500 grams weekly. Metabolic indices, physical activity and psychologic aspects will be assesses at baseline and the end of the intervention. Dietary adherence will be checked by 24hr recalls at day 0, 30 and 60. At the end of the study, we compare carriers with different alleles (AA+TA and TT) in two intervention groups to find out which calorie restriction is appropriate for each genotype. Significant p-value is less than 0.05.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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restricted diet
Mediterrasian diet according to adjusted ideal body weight with 500 calorie restriction
MediterrAsian diet
no other description
Non restricted diet
Mediterrasian diet according to adjusted ideal body weight without 500 calorie restriction
MediterrAsian diet
no other description
Interventions
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MediterrAsian diet
no other description
Eligibility Criteria
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Inclusion Criteria
* Ethnicity: Persian
Exclusion Criteria
* History of depression
* Pregnancy, trying to become pregnant or breast feeding
* Smoking
* Use of alcohol
* Significant weight loos during last two months (\>5 kilograms)
* being on a diet during last two months
* Use of any drug or supplement
20 Years
45 Years
ALL
Yes
Sponsors
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Shiraz University of Medical Sciences
OTHER
Responsible Party
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Mahsa Mehrdad
Ph.D Candidate
Locations
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Shiraz university of medical sciences
Shiraz, Fars, Iran
Countries
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Other Identifiers
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ir.sums.rec.1395.100
Identifier Type: -
Identifier Source: org_study_id
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