Long-term Outcomes of Superficial Esophageal Squamous Cell Carcinoma

NCT ID: NCT02908204

Last Updated: 2016-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-10-31

Brief Summary

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Tumor is the primary public health problem and the incidence of esophageal cancer showed the increasing trend in the past thirty years. According to the statistics in 2015, the new onset of esophageal cancer is about 477,900 yearly. The mainly pathologic type of esophageal cancer in China is esophageal squamous cell carcinomas, which accounts for more than 90% of patients in China. With the development of endoscopic technics, more and more patients choose to receive the endoscopic procedure rather than traditional surgery. However, the long-term efficacy and outcomes of patients with superficial esophageal squamous cell carcinoma received different interventions remained unclear. Thus, investigators aim to conduct a multi-center retrospective study to investigate the long term outcomes of superficial esophageal squamous cell carcinoma patients receiving endoscopic treatment and surgery.

Detailed Description

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Conditions

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Esophageal Neoplasms

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Endoscopic treatment

Patients underwent endoscopic treatment including Endoscopic Mucosal Resection (EMR), Endoscopic Submucosal Dissection (ESD), Multiband Mucosectomy (MBM), Endoscopic Mucosal Band Ligation(EMBL) and so on.

No interventions assigned to this group

Traditional surgery

Patients underwent traditional surgery

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients received endoscopic treatment because of the superficial esophageal disease and had the pathologic diagnosis of squamous cell carcinoma.

Exclusion Criteria

* Combined with other severe disease
* With a history of esophageal surgery
* Combined with other malignant disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

OTHER

Sponsor Role collaborator

Tongji Hospital

OTHER

Sponsor Role collaborator

The affiliated Hospital of Shihezi University

UNKNOWN

Sponsor Role collaborator

Shanghai Zhongshan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Shiyao Chen

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Zhongshan Hospital,

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Shiyao CHEN, PhD

Role: CONTACT

13601767310

Facility Contacts

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Xiaoquan HUANG, M.D.

Role: primary

18801733835

Other Identifiers

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SGZAHGX

Identifier Type: -

Identifier Source: org_study_id

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