Impact of Neutrophil Extracellular Traps on Tissue Plasminogen Activator Induced Thrombolysis in Acute Ischemic Stroke Patients
NCT ID: NCT02907736
Last Updated: 2018-03-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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WITHDRAWN
OBSERVATIONAL
2015-11-12
2017-07-01
Brief Summary
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The aim of this study is to assess the impact of NETs composition of thrombi retrieved during endovascular therapy in AIS patients on IV t-PA induced thrombolysis, clinical outcome and AIS etiologies.
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Detailed Description
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Conditions
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Study Design
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OTHER
CROSS_SECTIONAL
Eligibility Criteria
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Inclusion Criteria
* AIS secondary to a large vessel occlusion
* admitted for endovascular therapy.
Exclusion Criteria
* Patient opposition to participate in this study
18 Years
ALL
No
Sponsors
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Fondation Ophtalmologique Adolphe de Rothschild
NETWORK
Responsible Party
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Principal Investigators
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Jean-Philippe Désilles, MD
Role: PRINCIPAL_INVESTIGATOR
Fondation OPH A. de Rothschild
Mikael Mazighi, MD, PhD
Role: STUDY_CHAIR
Fondation OPH A. de Rothschild
Locations
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Fondation Ophtalmologique Adolphe de Rothschild
Paris, , France
Countries
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References
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Ducroux C, Di Meglio L, Loyau S, Delbosc S, Boisseau W, Deschildre C, Ben Maacha M, Blanc R, Redjem H, Ciccio G, Smajda S, Fahed R, Michel JB, Piotin M, Salomon L, Mazighi M, Ho-Tin-Noe B, Desilles JP. Thrombus Neutrophil Extracellular Traps Content Impair tPA-Induced Thrombolysis in Acute Ischemic Stroke. Stroke. 2018 Mar;49(3):754-757. doi: 10.1161/STROKEAHA.117.019896. Epub 2018 Feb 8.
Other Identifiers
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JDS_2015_45
Identifier Type: -
Identifier Source: org_study_id
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