Vitamin D and HbA1c Levels in Diabetic Patients With CKD

NCT ID: NCT02906319

Last Updated: 2016-09-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-09-30

Study Completion Date

2016-07-31

Brief Summary

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The purpose of this study is to determine the association between serum 25-hydroxyvitamin D and HbA1c levels in diabetic patients with chronic kidney disease. The investigators hypothesized that serum 25-hydroxyvitamin D levels were negatively correlated with HbA1c levels.

Detailed Description

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This was a cross sectional study using consecutive sampling methodology for participant recruitment. It was carried out at the specialized diabetic, renal, and general outpatient clinics in the University of Malaya Medical Centre (UMMC), Kuala Lumpur, Malaysia.

Serum 25(OH)D levels were determined by using direct chemiluminesent immunoassay (ADVIA Centaur XP; Siemens Healthcare Diagnostics, Tarrytown, New York, USA). Serum HbA1c levels were determined using high-pressure liquid chromatography (Variantâ„¢ II Turbo; Bio-Rad, Hercules, California, USA).

Data collected will be analyzed using Statistical Package for Social Sciences SPSS version 23.0 for Windows, version 23.0 (IBM Corp., Armonk, New York, USA).

Conditions

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Vitamin D Deficiency Diabetes Mellitus

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* eGFR 15-59 ml/min/1.73m2
* age ≥ 18 years old
* able to provide informed consent

Exclusion Criteria

* active infections
* autoimmune diseases
* malignancies
* on immunosuppressive therapy
* on vitamin D supplements
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Malaya

OTHER

Sponsor Role collaborator

Malaysian Society of Nephrology

UNKNOWN

Sponsor Role collaborator

Ng Yong Muh

OTHER

Sponsor Role lead

Responsible Party

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Ng Yong Muh

Dr

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Yong Muh Ng, MMed

Role: PRINCIPAL_INVESTIGATOR

University of Malaya

Other Identifiers

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201412-878

Identifier Type: -

Identifier Source: org_study_id

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