National Register of Oesophageal Atresia

NCT ID: NCT02883725

Last Updated: 2022-05-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

2500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-31

Study Completion Date

2025-12-31

Brief Summary

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The esophageal atresia is a group of birth defects including a break in continuity of the esophagus with or without persistent communication with the trachea (tracheoesophageal fistula), sometimes associated (from 50%) of other malformations (heart, kidney, digestive ...).

The current prognosis for this ailment is good. However he persists a mortality (\<10%) and significant morbidity, firstly related malformations (heart, kidney, for example), and secondly with particularly difficult anatomical forms (Forms long defect) .

The prevalence of this condition is estimated to be 1/2500 in 3000 live births, making an estimated ± 2,500 new cases over to 10 years in France.

The current project aims to set up a national registry (Metropolitan France and Dom Tom) to measure the prevalence of esophageal atresia among live births, phenotypic characteristics, the circumstances of their diagnosis, and their initial future at short-term during the first year of life, at which time occurs the vast majority of deaths and complications in this disease.

Detailed Description

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Conditions

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Esophageal Atresia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Esophageal atresia

data collection

Intervention Type OTHER

Interventions

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data collection

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* To be born in France
* To have a esophageal atresia

Exclusion Criteria

* To be born abroad
Maximum Eligible Age

1 Year

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Lille

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Frédéric Gottrand, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Lille

Locations

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CHU Félix-Guyon

Saint-Denis, La Réunion, France

Site Status RECRUITING

CHU Amiens-Picardie

Amiens, , France

Site Status RECRUITING

CHU d'Angers

Angers, , France

Site Status RECRUITING

CHRU Besançon

Besançon, , France

Site Status RECRUITING

CHU de Bordeaux

Bordeaux, , France

Site Status RECRUITING

CHRU Brest

Brest, , France

Site Status RECRUITING

HFME de Lyon

Bron, , France

Site Status RECRUITING

CHU de Caen

Caen, , France

Site Status RECRUITING

CHU de Clermont-Ferrand

Clermont-Ferrand, , France

Site Status RECRUITING

Hôpitaux Civils de Colmar

Colmar, , France

Site Status RECRUITING

CHI Créteil

Créteil, , France

Site Status RECRUITING

CHU Dijon Bourgogne

Dijon, , France

Site Status RECRUITING

CHU de Grenoble

La Tronche, , France

Site Status RECRUITING

AP-HP CHU Kremlin-Bicêtre

Le Kremlin-Bicêtre, , France

Site Status RECRUITING

CH Le Mans

Le Mans, , France

Site Status RECRUITING

CHRU,Hôpital Jeanne de Flandres

Lille, , France

Site Status RECRUITING

CHU de Limoges

Limoges, , France

Site Status RECRUITING

AP-HM La Timone

Marseille, , France

Site Status RECRUITING

AP-HM Nord

Marseille, , France

Site Status RECRUITING

CHRU de Montpellier

Montpellier, , France

Site Status RECRUITING

CHU de Nantes

Nantes, , France

Site Status RECRUITING

CHU de Nice

Nice, , France

Site Status RECRUITING

CHR d'Orléans

Orléans, , France

Site Status RECRUITING

AP-HP Armand Trousseau

Paris, , France

Site Status RECRUITING

AP-HP Necker-Enfants malades

Paris, , France

Site Status RECRUITING

AP-HP Robert-Debré

Paris, , France

Site Status RECRUITING

CHU de Poitiers

Poitiers, , France

Site Status RECRUITING

CHU de Reims

Reims, , France

Site Status RECRUITING

CHU de Rennes

Rennes, , France

Site Status RECRUITING

CHU de Rouen

Rouen, , France

Site Status RECRUITING

CHU de Saint-Etienne

Saint-Priest-en-Jarez, , France

Site Status RECRUITING

CHU de Strasbourg

Strasbourg, , France

Site Status RECRUITING

CHU de Toulouse

Toulouse, , France

Site Status RECRUITING

CHRU de Tours

Tours, , France

Site Status RECRUITING

CHU de Nancy

Vandœuvre-lès-Nancy, , France

Site Status RECRUITING

CHU de Pointe-à-Pitre

Pointe-à-Pitre, , Guadeloupe

Site Status RECRUITING

CHU de Martinique

Fort-de-France, , Martinique

Site Status RECRUITING

Countries

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France Guadeloupe Martinique

Central Contacts

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Frédéric Gottrand, MD,PhD

Role: CONTACT

References

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Lejeune S, Sfeir R, Rousseau V, Bonnard A, Gelas T, Aumar M, Panait N, Rabattu PY, Irtan S, Fouquet V, Le Mandat A, Cocci SN, Habonimana E, Lamireau T, Lemelle JL, Elbaz F, Talon I, Boudaoud N, Allal H, Buisson P, Petit T, Sapin E, Lardy H, Schmitt F, Levard G, Scalabre A, Michel JL, Jaby O, Pelatan C, De Vries P, Borderon C, Fourcade L, Breaud J, Arnould M, Tolg C, Chaussy Y, Geiss S, Laplace C, Drumez E, El Mourad S, Thumerelle C, Gottrand F. Esophageal Atresia and Respiratory Morbidity. Pediatrics. 2021 Sep;148(3):e2020049778. doi: 10.1542/peds.2020-049778. Epub 2021 Aug 19.

Reference Type DERIVED
PMID: 34413249 (View on PubMed)

Related Links

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Other Identifiers

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908362

Identifier Type: OTHER

Identifier Source: secondary_id

08.297

Identifier Type: OTHER

Identifier Source: secondary_id

Reg 2008

Identifier Type: -

Identifier Source: org_study_id

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