High-Frequency Repetitive Transcranial Magnetic Stimulation of the Right Dorsolateral Prefrontal Cortex in PTSD
NCT ID: NCT02873299
Last Updated: 2016-08-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
EARLY_PHASE1
37 participants
INTERVENTIONAL
2012-04-30
2014-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Treatment as usual
Treatment as usual, wait list control group
No interventions assigned to this group
rTMS at 10Hz
10 Hz rTMS of the right dorsolateral prefrontal cortex
10 Hz rTMS of the right dorsolateral prefrontal cortex
Ten sessions of 10 Hz rTMS of the right dorsolateral prefrontal cortex
rTMS at 20Hz
20 Hz rTMS of the right dorsolateral prefrontal cortex
20 Hz rTMS of the right dorsolateral prefrontal cortex
Ten sessions of 20 Hz rTMS of the right dorsolateral prefrontal cortex
Interventions
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10 Hz rTMS of the right dorsolateral prefrontal cortex
Ten sessions of 10 Hz rTMS of the right dorsolateral prefrontal cortex
20 Hz rTMS of the right dorsolateral prefrontal cortex
Ten sessions of 20 Hz rTMS of the right dorsolateral prefrontal cortex
Eligibility Criteria
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Inclusion Criteria
* Diagnosis of Post-Traumatic Stress Disorder as determined by the SCID
* CAPS score of at least 40
* Males or females between 18-65 years of age
* Willing to give up new psychotherapy or changes in psychiatric medications during the course of the TMS treatment.
Exclusion Criteria
* Patients with HDRS score ≥ 18
* A metallic implant in cranium (except the mouth)
* Patients with severe or unstable medical conditions, which in the opinion of the investigator would interfere with their progress or safety
* ECT treatment within the last three months
* Patients with a history of epilepsy
* Patients with neurological disorder leading to increased intracranial pressure
* Participation in a new course of psychotherapy during the 24 days of the study
* A new psychiatric medication within 6 weeks of enrolling in the study
* Changes in psychiatric medication within 2 weeks of starting the study
18 Years
65 Years
ALL
Yes
Sponsors
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United States Naval Medical Center, San Diego
FED
Responsible Party
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Principal Investigators
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Marc A Capobianco, MD, DFAPA
Role: PRINCIPAL_INVESTIGATOR
NMCSD
Locations
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NMCSD
San Diego, California, United States
Countries
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Other Identifiers
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NMCSD.2011.0025
Identifier Type: -
Identifier Source: org_study_id
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