Development of a Methodology to Design a High Order Sliding Mode Controller for Drug Dosage

NCT ID: NCT02864212

Last Updated: 2020-08-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-30

Study Completion Date

2021-12-31

Brief Summary

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The aim of this observational study is to create a data base to extract feature of fast-acting drugs that can be monitor in real time to design control strategies based on high order sliding mode controller to create a robust drug infusion system.

Detailed Description

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The aim of this observational study is to create a database to extract feature of fast-acting drugs that can be monitor in real time to design control strategies based on high order sliding mode controller to create a robust drug infusion system.

The observed drugs in this study are fast acting insulin, propofol and sodium nitroprusside.

The effect of insulin will be measured by a continuous glucose monitor, the effect of propofol by a bispectral index monitor and the the effect of sodium nitroprusside by a invasive blood pressure monitor.

Conditions

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Diabetes Hypertension Anesthesia

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Glucose monitoring

Glucose will be monitor in patients using fast-acting insulin.

No interventions assigned to this group

Depth of anesthesia monitoring

Depth of anesthesia will be monitor in patients undergoing cardiac surgery.

No interventions assigned to this group

Blood pressure monitoring

Invasive blood pressure will be monitor in patients undergoing cardiac surgery.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* American Society of Anesthesiologists (ASA) physical status I, II, II

Exclusion Criteria

* Impossibility to measure depth of anesthesia or invasive blood pressure. Impossibility of using glucose monitor.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Coordinación de Investigación en Salud, Mexico

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ana Gallardo, Dr

Role: PRINCIPAL_INVESTIGATOR

Investigator

Locations

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Unidad de Investigación Médica en Enfermedades Metabólicas IMSS

Mexico City, Mexico City, Mexico

Site Status

Countries

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Mexico

Other Identifiers

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R-2014-785-063

Identifier Type: -

Identifier Source: org_study_id

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