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The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients

NCT ID: NCT02859194

Last Updated: 2018-07-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-05-31

Study Completion Date

2016-10-14

Brief Summary

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ECMO(Extracorporeal membrane oxygenation) is being essential for cardiopulmonary failure patients. There are two types of ECMO, which is veno-veno (V-V) that can be used in respiratory failure patients and veno-arterial (V-A) that can be used in cardiac failure patients. V-A ECMO can also be used during lung transplantation, substitution of cardiopulmonary bypass, which can show sufficient performance during operation and better postoperative outcome. However, regarding V-A ECMO circulating from femoral vein to femoral artery, there is a pro blem of differential hypoxia which might influence coronary artery and head vessels. In this prospective study, the investigators are planning to put another ECMO catheter into internal jugular vein which takes a role of left to right shunt, to mitigate the hypoxia of coronary artery.

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Detailed Description

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Conditions

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Interstitial Pulmonary Fibrosis ARDS COPD (Chronic Obstructive Pulmonary Disease) Bronchiectasis Lymphangioleiomyomatosis Primary Pulmonary Hypertension ARDS (Acute Respiratory Distress Syndrome)

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Veno-veno-arterial ECMO group

Group Type EXPERIMENTAL

Veno-veno-arterial ECMO

Intervention Type PROCEDURE

Interventions

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Veno-veno-arterial ECMO

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1\. scheduled for double lung transplantation

Exclusion Criteria

1. patients who have history of coronary artery occlusive disease
2. patients with arrhythmia
Minimum Eligible Age

20 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institue, Yonsei Universiy College of Medicine

Seoul, , South Korea

Site Status

Countries

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South Korea

Other Identifiers

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4-2016-0124

Identifier Type: -

Identifier Source: org_study_id

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