Overactive Bladder in Elderly Patients- An Early Warning of Coronary Artery Disease

NCT ID: NCT02854813

Last Updated: 2017-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-31

Study Completion Date

2017-01-31

Brief Summary

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Investigators aimed to investigate the association between over active bladder and coronary artery disease as demonstrated on coronary angiography.

Detailed Description

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The close relationship has been demonstrated between pelvic ischemia and overactive bladder (OAB) in a study involving elderly patients. In this study, it has been found that pelvic ischemia has triggered OAB and it has been related with cardiac ischemia. The aim of this study was to delineate the correlation between OAB and the degree of coronary artery stenosis as demonstrated on coronary angiography.

Conditions

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Overactive Bladder Syndrome Coronary Artery Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1

Patients with a OAB-V8 score ≥8

No interventions assigned to this group

Group 2

Patients with a OAB-V8 score \<8

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients, whom were diagnosed to undergo coronary angiography in a center of cardiology

Exclusion Criteria

* a maximum flow rate of 15 ml. per second or less,
* residual volume of 100 cc or more,
* diabetes mellitus,
* neurologic disease,
* prostate or bladder cancer,
* renal failure,
* urinary tract infection,
* nephrolithiasis or pelvic surgery,
* patients with a history of percutaneous coronary intervention or coronary artery bypass grafting
Minimum Eligible Age

65 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ankara Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Muhammet Fatih Kilinc

M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ankara Training and Research Hospital

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Tarcan T, Azadzoi KM, Siroky MB, Goldstein I, Krane RJ. Age-related erectile and voiding dysfunction: the role of arterial insufficiency. Br J Urol. 1998 Dec;82 Suppl 1:26-33. doi: 10.1046/j.1464-410x.1998.0820s1026.x. No abstract available.

Reference Type BACKGROUND
PMID: 9883259 (View on PubMed)

De EJ, Hou P, Estrera AL, Sdringola S, Kramer LA, Graves DE, Westney OL. Pelvic ischemia is measurable and symptomatic in patients with coronary artery disease: a novel application of dynamic contrast-enhanced magnetic resonance imaging. J Sex Med. 2008 Nov;5(11):2635-45. doi: 10.1111/j.1743-6109.2008.00969.x. Epub 2008 Aug 26.

Reference Type BACKGROUND
PMID: 18761598 (View on PubMed)

Other Identifiers

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5192

Identifier Type: -

Identifier Source: org_study_id

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