Sildenafil Citrate in Frozen Embryo Transfer

NCT ID: NCT02845388

Last Updated: 2016-07-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-09-30

Study Completion Date

2016-06-30

Brief Summary

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Comparison between usage of Sildenafil citrate with estradiol valerate or estradiol valerate alone in endometrial preparation and outcome of frozen-thawed embryo transfer cycles.

Detailed Description

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Conditions

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Infertility

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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estradiol valerate

estradiol valerate 2mg every 12 hours orally starting from the second day of the menstrual cycle till reaching trilaminar endometrial pattern and endometrial thickness 8 mm or more

Group Type ACTIVE_COMPARATOR

estradiol valerate

Intervention Type DRUG

Sildenafil citrate and estradiol valerate

Sildenafil citrate 25 mg every 6 hours orally in combination with estradiol valerate 2mg every 12 hours orally starting from the second day of the menstrual cycle till reaching trilaminar endometrial pattern and endometrial thickness 8 mm or more

Group Type ACTIVE_COMPARATOR

Sildenafil citrate

Intervention Type DRUG

estradiol valerate

Intervention Type DRUG

Interventions

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Sildenafil citrate

Intervention Type DRUG

estradiol valerate

Intervention Type DRUG

Other Intervention Names

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Viagra

Eligibility Criteria

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Inclusion Criteria

* all cases have at least 2 good quality blastocysts available for transfer

Exclusion Criteria

* uterine structural abnormalities
* advanced uterine disease
* hydrosalpinx and pyosalpinx
Minimum Eligible Age

20 Years

Maximum Eligible Age

37 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Omar Ahmed El Sayed Saad

OTHER

Sponsor Role lead

Responsible Party

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Omar Ahmed El Sayed Saad

Resident of obstetric and gynecology in Shebin Elkom teaching hospital

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Alaa mohamed elghannam, professor

Role: STUDY_CHAIR

department of obstetric and gynacology Ain shams university

Other Identifiers

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Ainshams2015Omar

Identifier Type: -

Identifier Source: org_study_id

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