Working Memory Training for Chronic Neuropathic and Fibromyalgia Pain

NCT ID: NCT02824588

Last Updated: 2018-09-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

82 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-09-30

Study Completion Date

2018-09-02

Brief Summary

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The goal of this project is to investigate and improve executive control function in two distinct pain conditions, namely neuropathic pain and fibromyalgia (FM). It is hypothesized that there is a significant difference in the executive control function of patients with neuropathic pain and FM pain. It is also hypothesized that all participants with poor executive control functioning will report significant improvements in pain intensity, functioning and cognitive complaints following cognitive training. The study tests and influence the working memory concepts of inhibition, updating and flexibility through an experimental, cross-over treatment design.

To perform the experiment, we will recruit 160 participants (80 with neuropathic pain and 80 with FM) from the Departments of pain management and research at St Olav's University Hospital and Oslo University Hospital (OUS). The proposed design will be able to determine whether or not executive control, processing speed and memory function differs in two distinct populations of pain patients. Moreover, whether impairments are amended by computerized training.

Detailed Description

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Conditions

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Working Memory Deficits Neuropathic Pain Fibromyalgia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intervention

Working Memory Training

Group Type EXPERIMENTAL

Working Memory Training

Intervention Type BEHAVIORAL

Training mental flexibility

Control

Internet use

Group Type ACTIVE_COMPARATOR

Internet use

Intervention Type BEHAVIORAL

Used as control for time spent on computer

Interventions

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Working Memory Training

Training mental flexibility

Intervention Type BEHAVIORAL

Internet use

Used as control for time spent on computer

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Confirmed diagnosis of fibromyalgia or neuropathic pain
* Confirmed objective cognitive impairments on the CANTAB battery compared to IQ control

Exclusion Criteria

* Mania, suicidal ideation and/or active psychosis
* No objective cognitive impairments
* Personality disorders
* Pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

69 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oslo University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Henrik Børsting Jacobsen

Post Doctoral Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Oslo University Hospital

Oslo, , Norway

Site Status

Countries

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Norway

Other Identifiers

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2016/8442

Identifier Type: -

Identifier Source: org_study_id

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