Using an API to Commercialize an Evidence-Based Weight Loss Intervention

NCT ID: NCT02812264

Last Updated: 2020-07-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

209 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-07

Study Completion Date

2019-12-01

Brief Summary

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This study will test the effectiveness of a mobile application that uses an Application Program Interface (API) to distribute evidence-based weight loss interventions. Half of the participants will receive this API-based application, and the other half of the participants will use a non API-based application.

Detailed Description

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The purpose of this study is to test a weight loss app that uses an API to disseminate an evidence-based weight loss intervention. The investigators hypothesize that, over the course of 12 months, participants using the Leaner app will have lost more weight than those in the attention control group.

Participants (n=206) will be randomly assigned to use either the intervention app (intervention arm; n=103) or a weight loss app of their choosing (attention control arm; n=103) for 12 months. Assessments will take place at baseline, and 3, 6, and 12 months.

Statistical analysis: A linear mixed modeling approach will be used to test the hypothesis. Observed weight vs. time plots will be analyzed for all participants to discern general trends in weight change. The model will include an intervention effect, a time effect, an intervention by time interaction, and a random intercept.

In exploratory analysis, investigators will examine weight change across subgroups of interest; investigators will add the subgroup variable and its interaction with the intervention indicator to the primary model. All analyses will be evaluated at the 0.05 significance level.

Conditions

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Weight Loss Health Behavior

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators
Participants will not know which arm they have been randomized to. Additionally, the investigators will be blinded to participant assignment. Randomization will be completed by the program manager.

Study Groups

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API App

use of API weight loss mobile application for 12 months, plus fitness tracker and scale.

Group Type EXPERIMENTAL

API App

Intervention Type BEHAVIORAL

Mobile application that uses API technology to deliver evidence-based weight loss intervention. Includes syncing with wearable fitness tracker and scale

fitness tracker

Intervention Type BEHAVIORAL

fitness tracker to monitor physical activity and sleep patterns that is connected to transfer data to app

scale

Intervention Type BEHAVIORAL

Connected scale that will transfer weight information to app

Attention Control

use of non-API app for weight loss over 12 months, plus fitness tracker and scale.

Group Type ACTIVE_COMPARATOR

Non-API App

Intervention Type BEHAVIORAL

Mobile application that does not use API technology to deliver evidence-based weight loss intervention. Includes syncing with wearable fitness tracker and scale.

fitness tracker

Intervention Type BEHAVIORAL

fitness tracker to monitor physical activity and sleep patterns that is connected to transfer data to app

scale

Intervention Type BEHAVIORAL

Connected scale that will transfer weight information to app

Interventions

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API App

Mobile application that uses API technology to deliver evidence-based weight loss intervention. Includes syncing with wearable fitness tracker and scale

Intervention Type BEHAVIORAL

Non-API App

Mobile application that does not use API technology to deliver evidence-based weight loss intervention. Includes syncing with wearable fitness tracker and scale.

Intervention Type BEHAVIORAL

fitness tracker

fitness tracker to monitor physical activity and sleep patterns that is connected to transfer data to app

Intervention Type BEHAVIORAL

scale

Connected scale that will transfer weight information to app

Intervention Type BEHAVIORAL

Other Intervention Names

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wearable weight

Eligibility Criteria

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Inclusion Criteria

* informed consent
* between 21-65 years old
* BMI between 25-40 kg/m2
* ownership and use of an Android smartphone during past 6 months with no plans to change phone/service during study
* consent for research team to monitor app utilization

Exclusion Criteria

* use of weight loss medication
* prior or planned bariatric surgery
* psychiatric hospitalization in past 12 months
* pregnancy, nursing, or planned pregnancy during the study
* history of cardiovascular disease (CVD) event
* self-reported history of an eating disorder
* use of medication for diabetes mellitus
* mobility restrictions for which exercise is contraindicated
* history of a condition (e.g., lithium, steroids, anti-psychotics) that would affect weight measurement, for which weight loss is contraindicated
* current participation in another weight treatment study and/or recent weight loss \>10%
* investigator discretion for safety reasons
Minimum Eligible Age

21 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Coeus Health, LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Coeus Health Offices

State College, Pennsylvania, United States

Site Status

Countries

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United States

Other Identifiers

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4R44DK103519-02

Identifier Type: NIH

Identifier Source: org_study_id

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