Neural Mechanism of Cortisol Awakening Response Suppression Effect on Human High-order and Social Cognitions

NCT ID: NCT02799134

Last Updated: 2022-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

67 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-11-30

Study Completion Date

2017-04-30

Brief Summary

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CAR is short for cortisol awakening response. The neural mechanism of CAR effect on high-order cognition and social cognition is less known...

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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group1

take Dexamethasone at 22:00 on the first day, 0.5mg

Group Type EXPERIMENTAL

Dexamethasone

Intervention Type DRUG

group2

take Vitamin C at 22:00 on the first day, 0.5mg

Group Type PLACEBO_COMPARATOR

Vitamin C

Intervention Type DRUG

group3

take Dexamethasone at 15:00 on the second day, 0.5mg

Group Type OTHER

Dexamethasone

Intervention Type DRUG

Interventions

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Dexamethasone

Intervention Type DRUG

Vitamin C

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Healthy college students.

Exclusion Criteria

* Current or history of psychiatric or neurological illness.
* Current use of any medications.
Minimum Eligible Age

18 Years

Maximum Eligible Age

26 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Chinese Academy of Sciences

OTHER_GOV

Sponsor Role collaborator

Xuanwu Hospital, Beijing

OTHER

Sponsor Role collaborator

qinshaozheng

OTHER

Sponsor Role lead

Responsible Party

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qinshaozheng

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Shaozheng Qin, Doctor

Role: STUDY_CHAIR

Beijing Normal University

Locations

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Beijing Normal University

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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ICBIR_A_0098_002

Identifier Type: -

Identifier Source: org_study_id

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