Postoperatively Treated Patients With Lower Limb Fracture With or Without an Anti-gravity Treadmill

NCT ID: NCT02790229

Last Updated: 2019-06-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

73 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-08-31

Study Completion Date

2019-06-17

Brief Summary

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The presented study is designed to prove efficacy of the anti-gravity treadmill (alter G®) compared to a standard rehabilitation protocol in patients with tibial plateau or ankle fractures with six weeks of partial weight bearing.

Detailed Description

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Conditions

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Muscle Degeneration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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anti-gravity treadmill arm

Treatment with anti-gravity treadmill (alter G®)

Group Type EXPERIMENTAL

anti-gravity treadmill (alter G®)

Intervention Type OTHER

Patients in the experimental arm will be treated with manual lymphatic drainage, cryotherapy and a fixed protocol of training in an anti-gravity treadmill (alter G®). The protocol is designed parallel to standard physiotherapy with a frequency of two to three times a week with duration of about 20 minutes for six weeks.

control arm

Treatment with standardized physiotherapy

Group Type OTHER

standardized physiotherapy

Intervention Type OTHER

Patients in the control arm will be treated with manual lymphatic drainage, cryotherapy and 20 minutes of physiotherapy two to three times a week for six weeks. Physiotherapy will be done according to a standardized protocol.

Interventions

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anti-gravity treadmill (alter G®)

Patients in the experimental arm will be treated with manual lymphatic drainage, cryotherapy and a fixed protocol of training in an anti-gravity treadmill (alter G®). The protocol is designed parallel to standard physiotherapy with a frequency of two to three times a week with duration of about 20 minutes for six weeks.

Intervention Type OTHER

standardized physiotherapy

Patients in the control arm will be treated with manual lymphatic drainage, cryotherapy and 20 minutes of physiotherapy two to three times a week for six weeks. Physiotherapy will be done according to a standardized protocol.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients with a postoperative partial weight bearing after tibial plateau or ankle fracture.
* man and woman of an age between 18 and 65

Exclusion Criteria

* Body weight more than 100kg
* serious illness or poor general health as judged by physician that may influence the rehabilitation
* open fractures (\>1° according to Gustilo and Anderson)
* surgical site infection
* pregnancy
* neuromuscular disorders or preexisting muscle atrophy.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ambulantes Reha Centrum Gruppe, Germany

UNKNOWN

Sponsor Role collaborator

Hospital St.Georg gGmbH; Clinic of Trauma, Orthopedic and septic Surgery, Leipzig, Germany

UNKNOWN

Sponsor Role collaborator

University of Leipzig

OTHER

Sponsor Role lead

Responsible Party

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Dr. med. Ralf Henkelmann

Dr. med. Ralf Henkelmann

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Leipzig, Clinic of Orthopedic, Trauma and Plastic Surgery

Leipzig, Saxony, Germany

Site Status

Klinikum St. Georg gGmbH

Leipzig, Saxony, Germany

Site Status

Countries

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Germany

References

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Webber SC, Horvey KJ, Yurach Pikaluk MT, Butcher SJ. Cardiovascular responses in older adults with total knee arthroplasty at rest and with exercise on a positive pressure treadmill. Eur J Appl Physiol. 2014 Mar;114(3):653-62. doi: 10.1007/s00421-013-2798-1. Epub 2013 Dec 22.

Reference Type BACKGROUND
PMID: 24362964 (View on PubMed)

Suetta C, Frandsen U, Mackey AL, Jensen L, Hvid LG, Bayer ML, Petersson SJ, Schroder HD, Andersen JL, Aagaard P, Schjerling P, Kjaer M. Ageing is associated with diminished muscle re-growth and myogenic precursor cell expansion early after immobility-induced atrophy in human skeletal muscle. J Physiol. 2013 Aug 1;591(15):3789-804. doi: 10.1113/jphysiol.2013.257121. Epub 2013 Jun 3.

Reference Type BACKGROUND
PMID: 23732643 (View on PubMed)

Saxena A, Granot A. Use of an anti-gravity treadmill in the rehabilitation of the operated achilles tendon: a pilot study. J Foot Ankle Surg. 2011 Sep-Oct;50(5):558-61. doi: 10.1053/j.jfas.2011.04.045. Epub 2011 Jun 23.

Reference Type BACKGROUND
PMID: 21703879 (View on PubMed)

Takacs J, Leiter JR, Peeler JD. Novel application of lower body positive-pressure in the rehabilitation of an individual with multiple lower extremity fractures. J Rehabil Med. 2011 Jun;43(7):653-6. doi: 10.2340/16501977-0806.

Reference Type BACKGROUND
PMID: 21584484 (View on PubMed)

Peeler J, Christian M, Cooper J, Leiter J, MacDonald P. Managing Knee Osteoarthritis: The Effects of Body Weight Supported Physical Activity on Joint Pain, Function, and Thigh Muscle Strength. Clin J Sport Med. 2015 Nov;25(6):518-23. doi: 10.1097/JSM.0000000000000173.

Reference Type BACKGROUND
PMID: 25647537 (View on PubMed)

Moore MN, Vandenakker-Albanese C, Hoffman MD. Use of partial body-weight support for aggressive return to running after lumbar disk herniation: a case report. Arch Phys Med Rehabil. 2010 May;91(5):803-5. doi: 10.1016/j.apmr.2010.01.014.

Reference Type BACKGROUND
PMID: 20434621 (View on PubMed)

McNeill DK, de Heer HD, Bounds RG, Coast JR. Accuracy of unloading with the anti-gravity treadmill. J Strength Cond Res. 2015 Mar;29(3):863-8. doi: 10.1519/JSC.0000000000000678.

Reference Type BACKGROUND
PMID: 25226319 (View on PubMed)

Hoffman MD, Donaghe HE. Physiological responses to body weight--supported treadmill exercise in healthy adults. Arch Phys Med Rehabil. 2011 Jun;92(6):960-6. doi: 10.1016/j.apmr.2010.12.035.

Reference Type BACKGROUND
PMID: 21621673 (View on PubMed)

Cutuk A, Groppo ER, Quigley EJ, White KW, Pedowitz RA, Hargens AR. Ambulation in simulated fractional gravity using lower body positive pressure: cardiovascular safety and gait analyses. J Appl Physiol (1985). 2006 Sep;101(3):771-7. doi: 10.1152/japplphysiol.00644.2005. Epub 2006 Jun 15.

Reference Type BACKGROUND
PMID: 16777997 (View on PubMed)

Henkelmann R, Schneider S, Muller D, Gahr R, Josten C, Bohme J. Outcome of patients after lower limb fracture with partial weight bearing postoperatively treated with or without anti-gravity treadmill (alter G(R)) during six weeks of rehabilitation - a protocol of a prospective randomized trial. BMC Musculoskelet Disord. 2017 Mar 14;18(1):104. doi: 10.1186/s12891-017-1461-0.

Reference Type DERIVED
PMID: 28288613 (View on PubMed)

Other Identifiers

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FR-0244

Identifier Type: -

Identifier Source: org_study_id

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